Tazverik (Tazemetostat)

  • Brand Name: Tazverik
  • Innovator Brand Name: Tazverik
  • API: Tazemetostat
  • Dosage Form: 240 Tablets
  • Strength: 200mg
  • Manufacturer Name: Epizyme, Inc.
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Description

Tazverik Uses

Tazverik (Tazemetostat 200mg) is a methyltransferase inhibitor used for the treatment of:

  • Adults and pediatric patients aged 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.
  • Adult patients with relapsed/refractory follicular lymphoma whose tumors are positive for an EZH2 mutation as detected by an FDA-approved test and who have received at least 2 prior systemic therapies.
  • Adult patients with relapsed/refractory follicular lymphoma who have no satisfactory alternative treatment options.

Dosage: The recommended dosage of Tazemetostat is 800 mg orally twice daily with or without food until the disease is progressive or unacceptable toxicity occurs. Swallow tablets whole. Do not cut, crush, or chew tablets. Do not take an additional dose if a dose is missed or vomiting occurs after Tazemetostat, but continue with the next scheduled dose.

Side Effects: The most commonly reported tazemetostat side effects (incidence ≥ 20%) in patients with epithelioid sarcoma include:

  • pain
  • fatigue
  • nausea
  • vomiting
  • constipation
  • decreased appetite

The most commonly reported tazemetostat side effects (incidence ≥ 20%) in patients with follicular lymphoma include:

  • fatigue
  • musculoskeletal pain
  • nausea
  • abdominal pain
  • upper respiratory tract infection

Warnings and Precautions:

  • Monitor patients with tazverik 200 mg tablets for long-term for the development of secondary malignancies.
  • Verify the pregnancy status of females of reproductive potential prior to initiating therapy with tazverik tablets, as it can cause fetal harm if administered to pregnant women.
  • Women should not breastfeed during treatment with Tazemetostat and for 1 week following the final dose. Males with female partners of reproductive age or potential to use effective contraception during treatment with tazemetostat tablets and for at least 3 months after the final dose.
  • Patients receiving treatment with tazemetostat should avoid St. John’s wort, grapefruit, and grapefruit juice while on the therapy.

More info

Storage: Do not store above 30°C (86°F). Store at room temperature away from the moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative. Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship the TAZVERIK at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality as well as delivery for the TAZVERIK Tablets. Buying Procedure: In order to buy TAZVERIK, you can contact us at our TOLL-FREE Number: 1800 889 1064 or on WhatsApp number +919310090915 or an Email to us at: info@theindianpharma.com along with the legitimate ID Proof, Standard Prescription and Medical Reports. Conclusions: The FDA approval of Tazemetostat Tablets, an oral methyltransferase inhibitor, provides the first pharmacologic treatment option specifically for patients with epithelioid sarcoma. In addition, later in the year of 2020, the FDA approved tazemetostat to treat patients with relapsed/refractory follicular lymphoma. According to the EZH-202 pivotal clinical trial, tazemetostat therapy demonstrated a 15% ORR in patients with epithelioid sarcoma. Moreover, 67% of patients who responded to tazemetostat therapy sustained their response for ≥6 months in that study.

FAQ

What is Tazverik? Tazverik is a prescription medication approved for the treatment of patients with:
  •  epithelioid sarcoma.
  •  follicular lymphoma.
When was Tazverik FDA approved? On Jan 23, 2020, Tazverik was approved by the US Food and Drug Administration. What does Tazverik contain as an active substance? The medication Tazverik specifically contains the active substance Tazemetostat. What type of medication is Tazemetostat? Tazemetostat is a targeted therapy. It is classified as an EZH2 inhibitor or a histone methyltransferase inhibitor. How much does tazverik cost? The tazverik price in India usually can vary depending on the wholesaler/pharmacy you visit. Tazverik is available as a brand name drug only, a generic version is not yet available. What is the best price for Tazemetostat? Please contact Toll-free: +91 1800 889 1064 |+919310090915 for tazemetostat price in India. We take the guarantee of quality and delivery anywhere in the world as per the buyer’s requirements. Can I get Tazverik (Tazemetostat) even if I am not based in India? The Indian Pharma helps patients in accessing or importing Tazverik (Tazemetostat), not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country.
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