Velpanat (Sofosbuvir + Velpatasvir)

Facts of VELPANAT(sofosbuvir velpatasvir)

  • Brand Name: VELPANAT
  •  Medicine Name: Sofosbuvir + Velpatasvir
  • Company Name: Natco Pharma.
  • Supplied as: (Sofosbuvir 400 mg + Velpatasvir 100 mg) as 28 tablets in one pack
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What is Velpanat used for:

Velpanat (Sofosbuvir Velpatasvir), is a fixed-dose combination medication recommended for treating hepatitis C in adult patients. This medication combines sofosbuvir 400 mg and velpatasvir 100 mg. It is specifically more than 90% effective for the hepatitis C genotypes 1 through 6. It is also recommended for hepatitis C in those who also have cirrhosis or HIV/AIDS.


Velpanat one tablet (sofosbuvir 400 mg and velpatasvir 100 mg) should be taken orally at about the same time each day, either with or without food. Sofosbuvir and velpatasvir tablets should be swallowed whole with water. Avoid the consumption of opened, broken, or chewed tablets.

Side effects of Velpanat:

Sometimes Velpanat may leave a few most common adverse reactions include: fatigue, shortness of breath, anemia, nausea, not feeling well, chest pains, headache, insomnia and diarrhea.

Warnings and Precautions

  • Before taking this drug inform your healthcare provider if you have liver problems other than hepatitis C infection, have severe kidney problems or you are on dialysis.
  • If Velpanat is used with the ribavirin, the warnings, as well as precautions for ribavirin, should apply to this combinational regimen. Please refer to the full prescribing information of ribavirin.
  • Patients who experience symptoms of the bradycardia must seek medical evaluation right away. Symptoms may include tiredness, shortness of breath, near-fainting or fainting, dizziness, malaise, weakness, confusion, memory problems or chest pain.
  • Fatal cardiac arrest has been reported in such patients who consume amiodarone who was coadministered a sofosbuvir containing regimen (Harvoni).
  • The combination regimen of velpanat and ribavirin is contraindicated in such patients for whom ribavirin is strictly contraindicated.
  • Dosage recommendation should not be made for the patients with the end stage renal disease or severe renal impairment.
  • Sofosbuvir and velpatasvir should be avoided if you are pregnant or planning to become pregnant.
  • It is unknown if this medicine is safe and effective in children who are under 18 years of age.
  • Do not take this medication if you’re breastfeeding.
  • It is crucial that you do not miss or skip doses of Velpanat during the treatment.
  • If you consume too much Velpanat, call your healthcare professional or go to the nearest hospital emergency room right away.

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How Supplied/Storage and Handling:

Care should be exercised in the handling of VELPANAT. Velpanat tablets should not be opened or crushed. Store below 30 °C (86 ºF). Dispense only in the original container.

Alternate Brands of Sofosbuvir and velpatasvir Tablets:

  • Myhep All Tablet (Mylan Pharmaceuticals Pvt Ltd)
  • Velasof Tablet (Hetero Healthcare Ltd)
  • Sovihep V Tablet (Cadila Healthcare Ltd (Zydus)
  • Hepcvel Tablet (Cipla Ltd)
  • Velpacruz S Tablet (Torrent Pharmaceuticals Ltd)
  • Resof Total Tablet (Dr Reddy’S Laboratories Ltd)
  • Sofocure V Tablet (Emcure Pharmaceuticals Ltd)
  • Velpanat Tablet (Natco Pharma Ltd)

Commonly Asked Questions

What is Sofosbuvir-Velpatasvir used for?

Velpanat is a fixed-dose combination of sofosbuvir and velpatasvir, a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor, and velpatasvir, an HCV NS5A inhibitor, and is indicated for the treatment of patients (adults) with chronic HCV genotype 1, 2, 3, 4, 5 or 6 infection.

How to use a Velpanat tablet?

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Velpanat Tablet may be taken with or without food, but it is better to take it at a fixed time.

What to do in case of Overdose?

There is no specific antidote for overdose with Velpanat. If overdose occurs the patient must be monitored for evidence of toxicity under the healthcare care team.

What to do if I missed the Dose?

In missed dose circumstances, take the missed dose another day. Do not try to take a missed dose on the same day in order to catch up the cycle.

Where can I Buy VELPANAT (Sofosbuvir + Velpatasvir) 400 mg and 100 mg?

The Indian Pharma connects the buyer with the supplier who can ship VELPANAT to any country of the world as per the buyer’s requirement and Government regulations of the country. VELPANAT is manufactured by Natco Pharma. The Indian Pharma provides options for choosing exporter and supplier of cancer treatment medicines. We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.