Uses of Medication: Mitomycin is a chemotherapeutic agent indicated to treat upper gastrointestinal cancers such as esophageal carcinoma, breast cancers, anal cancer, as well as by bladder instillation for superficial bladder tumors.
Dosage: Mitomycin injection should be recommended intravenously only, using a lot of care to avoid the compound’s extravasation. If you have accidentally taken an excess dose, you may experience nausea, fever, vomiting, and blood disorders. Your healthcare provider may instruct you about supportive treatment for any symptoms that can appear. Talk to your healthcare providers for an appropriate and fresh dosing schedule in case of a missed dose.
Treatment Reactions: The most commonly reported adverse effects of Mitomycin are as follows:
- shortness of breath
- dry cough
- inspiratory crackles
- skin rashes
- irritation of the skin
- swelling as well as painful redness on the palms and soles
- renal dysfunction
- increased levels of creatinine in the blood
- inflammation of connective tissue
Warnings and Precautions:
- Before taking this drug as an injection or infusion into the vein, a blood test, check of kidney, lung, and liver function must be recommended.
- This drug should be administered with extreme caution in patients with significant impairment of renal function.
- Patients taking Mitomycin must be observed for evidence of renal toxicity.
- Healthcare professionals used this medicine in patients with serum creatinine greater than 1.7 mg %.
- Careful attention must be imposed to fluid balance, and overhydration should be avoided.
- The patient should be instructed of the potential toxicity of this drug, specifically the bone marrow depression.
- Breast-feeding should be discontinued before you start to use Mitomycin.