Mitotane

Brand Name: Lysodren
Innovator Brand Name: Lysodren
API: Mitotane
Packaging: Tablets
Strength: 500 mg
Manufacturer Name: Bristol-Myers Squibb

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Description

Mitotane Uses

Lysodren (Mitotane) is an adrenal cytotoxic agent used for the treatment of inoperable, functional or nonfunctional, adrenal cortical carcinoma.

Dosage: The recommended initial mitotane dose is 2 to 6 g orally, in three or four divided doses per day. Swallow the tablets with a glass of water during meals containing fat-rich food. Increase the doses incrementally in order to achieve a blood concentration of 14-20 mg/L, or as tolerated. Inform your healthcare team promptly if you have accidentally administered more dose than you should or if a child has accidentally swallowed some. If you miss a dose, just administer the next dose as scheduled. Never take a double dose in order to make up for the missed/forgotten one.

Side Effects: The most commonly reported mitotane side effects include:

  • Anorexia
  • Nausea
  • Vomiting
  • Diarrhea
  • Depression
  • Dizziness
  • Rash

Warnings and Precautions:

  • Patients are advised to discontinue the mitotane 500mg in the case of shock or severe trauma and contact their healthcare professional immediately.
  • Premenopausal women are advised to seek medical care in case they have gynecological symptoms such as vaginal bleeding/pelvic pain.
  • Females of reproductive potential are advised about the potential risk to a fetus and to inform their doctor of a known/suspected pregnancy.
  • Advise females who are nursing not to breastfeed while on mitotane 500mg therapy.
  • Hepatic impairment can interfere with the metabolism of mitotane and the drug may accumulate. Administer lysodren 500 with caution to patients with hepatic impairment.
  • CNS toxicity, including lethargy, sedation, and vertigo, occurs with mitotane therapy. Mitotane plasma concentrations exceeding 20 mcg/mL are related with a greater incidence of toxicity.
  • The lysodren 500 therapy has a major influence on the ability to drive and use machines. Ask your healthcare professional for advice.

More info

Storage: Store Lysodren (Mitotane) bottles at temperature 25°C (77°F); excursions permitted between 15°C and 30°C (59°F to 86°F).

Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship the LYSODREN at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality as well as delivery for the LYSODREN Tablets.

Buying Procedure: In order to buy LYSODREN, you can contact us at our Toll-free number 1800 889 1064 or on WhatsApp number +919650877511 or an Email to us at: info@theindianpharma.com along with the legitimate ID Proof, standard Prescription and Medical Reports.

Conclusion: Following comprehensive review, current outcomes suggest that the adjuvant mitotane significantly reduces the recurrence rate as well as mortality following resection of adrenal cortical carcinoma in patients without distant metastasis, but these outcomes need further demonstration from the prospective controlled trials.

FAQ

What is Lysodren?
Lysodren is a steroidogenesis inhibitor and cytostatic antineoplastic medication used in the treatment of adrenocortical carcinoma and Cushing’s syndrome.

What does Lysodren contain as an active substance?
The medication Lysodren specifically contains the active substance Mitotane.

Is Mitotane a chemotherapy?
Yes, Mitotane is a chemotherapy drug. It is also called Lysodren. ( Lysodren is a brand name)

How is Mitotane supplied?
Mitotane is supplied as Tablets, 500 mg for the oral administration.

How much does lysodren cost?
The lysodren 500 mg price in India usually may vary depending on the wholesaler/pharmacy you visit and of course the brand you choose. ( There is no any other brand name available for this drug)

What is the best price for Mitotane?
Please contact Toll-free: +91 1800 889 1064|+919650877511 for mitotane price in India. We take the guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.

Can I get Lysodren (Mitotane) even if I am not based in India?
The Indian Pharma helps patients in accessing or importing Lysodren (Mitotane), not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country.

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