Bleocel (Bleomycin)

Facts of BLEOMYCIN

  • Brand Name: BLEOCEL
  • Medicine Name: Bleomycin Sulfate
  • Company Name: Celon Laboratories Ltd.
  • Pack Size: Single Vial of 15 IU
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Description

Bleomycin and its uses:

BLEOMYCIN Sulfate should be considered a palliative treatment. It has been shown to be useful in the management of the following neoplasms either as a single agent or in proven combinations with other approved chemotherapeutic agents:

  • Squamous Cell Carcinoma- Head and neck (including mouth, tongue, tonsil, nasopharynx, oropharynx, sinus, palate, lip, buccal mucosa, gingivae, epiglottis, skin, larynx), penis, cervix, and vulva.
  • Lymphomas- Hodgkin’s disease, non-Hodgkin’s lymphoma.
  • Testicular Carcinoma- Embryonal cell, choriocarcinoma, and teratocarcinoma.
  • Malignant Pleural Effusion- BLEOCEL is effective as a sclerosing agent for the treatment of malignant pleural effusion and the prevention of recurrent pleural effusions.

Dosage:

Bleomycin should be given by intramuscular, subcutaneous, intrapleural or intravenous routes.

  • Squamous cell carcinoma, non-Hodgkin’s lymphoma, testicular carcinoma: The recommended dose as 0.25 to 0.50 units/kg (10 to 20 units/m2) should be given intravenously, intramuscularly, or subcutaneously weekly or twice weekly.
  • Hodgkin’s disease: The recommended dose as 0.25 to 0.50 units/kg (10 to 20 units/m2) should be given intravenously, intramuscularly, or subcutaneously weekly or twice weekly. After response of 50%, a maintenance dose of five units weekly or one unit daily can be recommended intramuscularly or intravenously.
  • Malignant Pleural Effusion: The recommended dose of 60 units should be administered as a single dose bolus intrapleural injection.

Treatment Reactions:

The most commonly reported adverse reactions of bleomycin injection ip 15 units are as follows:

  • interstitial pneumonitis
  • pulmonary fibrosis
  • laboured breathing
  • loss of appetite
  • weight loss
  • nausea
  • vomiting
  • mucositis
  • stomatitis
  • inflammatory redness of the skin
  • itching
  • striae (stretch marks)
  • blistering
  • hyperpigmentation
  • tenderness of the fingertips
  • hyperkeratosis
  • hair loss

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Warning and Precautions:

  • The bleomycin injection should be avoided in patients who have demonstrated a hypersensitive or an idiosyncratic reaction to it.
  • Breastfeeding should be avoided due to the potential secretion into the breast milk.
  • Patients receiving bleomycin injection should be carefully observed and frequently during/after the therapy.
  • It (bleomycin sulfate) always should be used with caution in patients with the significant impairment of the renal function or compromised pulmonary function.
  • Hepatic or renal toxicity, beginning as a deterioration in renal or liver function tests, have been reported. These toxicities can occur at any time post initiation of the therapy.
  • Care should be taken in dose selection in elderly patients with the decreased renal function, and it can be helpful in order to monitor the renal function.

How Supplied/Storage and Handling:

Care should be exercised in the handling of BLEOCEL. The bleocel injection should be stored in a refrigerator (2°C – 8°C). For single use only. Discard any residues. The reconstituted/diluted product must be used immediately.

Alternate Brands of Bleomycin:

The alternate brands of bleomycin are:

  • Bleocip 15Iu Injection (Cipla Ltd)
  • Bleocel 15Iu Injection (Celon Laboratories Ltd)

Commonly Asked Questions

1. What is the best price of BLEOCEL (Bleomycin Sulfate 15 IU)?

The bleomycin injection price is decent. Please contact +91 8130290915 for Bleocel price in India We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.

2. Where can I Buy Bleomycin Injection?

The Indian Pharma connects the buyer with the supplier who can ship BLEOCEL or BLEOMYCIN to any country of the world as per the buyer’s requirement and Government regulations of the country. BLEOCEL is manufactured by Celon Lab. The Indian Pharma provides options for choosing exporter and supplier of cancer treatment medicines. We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.

3. How order will be confirmed?

The order will be confirmed only after the receipt of • Valid prescription of Clinician • Import permit if applicable

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