Margenza (Margetuximab)

  • Brand Name: Margenza
  • Innovator Brand Name: Margenza
  • API: Margetuximab-cmkb
  • Dosage Form: 1 Vial (Per Box)
  • Strength: 250mg/10ml
  • Manufacturer Name: MacroGenics
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Description

Margenza Medication:

Margenza (Margetuximab-cmkb) is a HER2/neu receptor antagonist used, in combination with chemotherapy, to treat adult patients with metastatic HER2¬ positive breast cancer who have received two or more prior anti-HER2 regimens, at least one of which was for metastatic disease.

Dosage: The recommended dose of margenza is 15 mg/kg, administered as an intravenous infusion every 3 weeks (21-day cycle) until the disease is progressive or unacceptable toxicity occurs. Administer margenza as an intravenous infusion at 15 mg/kg over 120 minutes for the initial dose, then over a minimum of 30 minutes every 3 weeks for all subsequent doses. On days when both margenza and chemotherapy are to be administered, margenza may be administered immediately after chemotherapy completion.

Side Effects: The most commonly reported margetuximab side effects in combination with chemotherapy include:

  • Fatigue/asthenia
  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Headache
  • Pyrexia
  • Alopecia
  • Abdominal pain
  • Peripheral neuropathy
  • Arthralgia/myalgia
  • Cough
  • Decreased appetite
  • Dyspnea
  • Extremity pain
  • Infusion-related reactions
  • Palmar-plantar erythrodysesthesia

Warnings and Precautions:

  • Patients with margenza dose should contact a health specialist promptly for new onset or worsening shortness of breath, swelling of the ankles/legs, cough, swelling of the face, sudden weight gain, palpitations, dizziness or loss of consciousness.
  • Monitor patients for IRRs during margenza uses and as clinically indicated following completion of infusion.
  • Conduct cardiac assessment, including history, physical examination, and determination of LVEF through echocardiogram or MUGA scan.
  • Verify pregnancy status of respective women of reproductive potential prior to initiation of margetuximab injection.
  • Margetuximab can be responsible for causing fetal harm when administered to a pregnant woman.

More info

Storage: Store vials refrigerated at 2°C to 8°C (36°F to 46°F) in original carton in order to protect from light until time of use. Neither freeze nor shake it. Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship the MARGENZA at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality as well as delivery for the MARGENZA Injections. Buying Procedure: In order to buy MARGENZA, you can contact us at our Toll-free number 1800 889 1064 or on WhatsApp number +919310090915 or an Email to us at: info@theindianpharma.com along with the legitimate ID Proof, standard Prescription and Medical Reports. Conclusion: Margetuximab is well tolerated with promising activity in patients with Breast Cancer who have failed prior HER-2 therapies and in patients with HER2+ tumors for which H is considered ineffective.

FAQ

What is Margenza? Margenza is specifically a chimeric IgG monoclonal antibody against HER2 aimed to treat cancer. What does Margenza contain as an active substance? The medication Margenza specifically contains the active substance margetuximab-cmkb. How is Margetuximab supplied? Margetuximab is supplied as Injection: 250 mg/10 mL (25 mg/mL) in a single-dose vial for intravenous infusion. How much does margenza cost? The margenza price in India usually can vary depending on the wholesaler/pharmacy you visit. Margenza is available as a brand name drug only, a generic version is not yet available. What is the best price for Margetuximab? Please contact Toll-free: +91 1800 889 1064|+919310090915 for margetuximab price in India. We take the guarantee of quality and delivery anywhere in the world as per the buyer’s requirements. Can I get Margenza (Margetuximab-cmkb) even if I am not based in India? The Indian Pharma helps patients in accessing or importing Margenza (Margetuximab-cmkb), not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country.

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