Pemazyre (pemigatinib)

  • Brand Name: Pemazyre
  • Innovator Brand Name: Pemazyre
  • API: Pemigatinib
  • Dosage Form: 14 Tablets
  • Strength: 4.5/9/13.5mg
  • Manufacturer Name: Incyte Corporation
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Pemazyre Uses

Pemigatinib tablet is a kinase inhibitor used for the treatment of adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma (bile duct cancer) with a fibroblast growth factor receptor 2 (FGFR2) fusion or other rearrangement as detected by an FDA-approved test.

Dosage: The recommended dosage of Pemigatinib is 13.5 mg orally once daily for 14 consecutive days followed by 7 days off therapy, in 21-day cycles. Continue treatment until the disease is progressive or unacceptable toxicity occurs. Take the pemigatinib tablet dosage with or without food at approximately the same time every day. Swallow your tablets whole. Do not crush/chew/split/dissolve tablets. In case the patient misses a dose of Pemigatinib by four or more hours or if vomiting occurs, resume dosing with the next scheduled dose.

Side Effects: The most commonly reported pemazyre side effects (incidence ≥ 20%) include:

  • alopecia
  • diarrhea
  • nail toxicity
  • fatigue
  • dysgeusia
  • nausea
  • constipation
  • stomatitis
  • dry eye
  • dry mouth
  • decreased appetite
  • vomiting
  • arthralgia
  • abdominal pain
  • back pain
  • dry skin
  • hypophosphatemia

Warnings and Precautions:

  • Perform a comprehensive ophthalmological examination including OCT prior to initiation of pemazyre 4.5 mg tablet and every 2 months for the first 6 months and every 3 months thereafter during treatment.
  • Patients taking treatment with pemazyre tablet fda label medication should be monitored for hyperphosphatemia and initiate a low phosphate diet when serum phosphate level is > 5.5 mg/dL.
  • Females should inform their health specialist if they are pregnant or become pregnant. Pemazyre 4.5 mg tablets can cause fetal harm if administered to pregnant women.
  • Males with female partners of reproductive potential should use effective contraception during treatment with pemazyre dosage and for 1 week following the final dose.
  • Patients should not breastfeed during treatment with Pemigatinib tablet and for 7 days following the final dose.

More Info

Storage: Store pemigatinib tablets at room temperature 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship the PEMAZYRE at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality as well as delivery for the PEMAZYRE Tablets. Buying Procedure: In order to buy PEMAZYRE, you can contact us at our TOLL-FREE Number: 1800 889 1064 or on WhatsApp number +919310090915 or an Email to us at: along with the legitimate ID Proof, Standard Prescription and Medical Reports. Conclusions: Patients with advanced cholangiocarcinoma have few treatment options and poor prognosis. The new kinase inhibitor named pemigatinib is the first FDA-approved targeted therapy to treat adults with advanced cholangiocarcinoma and the FGFR2 biomarker, offering patients a new treatment option. It had an acceptable and manageable toxicity. It is well tolerated and demonstrates a possible anti-cancer benefit.


What is Pemazyre? Pemazyre is the first FDA-approved prescription medicine that is widely used to treat adults with bile duct cancer (cholangiocarcinoma) that has spread or cannot be eliminated or removed by surgery:
  • who have already taken a previous therapy, and
  • whose tumor has a certain type of abnormal “FGFR2” gene.
When was Pemazyre FDA approved? In April 2020, Pemazyre was approved by the US Food and Drug Administration. Is Pemazyre chemotherapy? No, Pemazyre is a targeted-treatment for bile duct cancer or cholangiocarcinoma. What does Pemazyre contain as an active substance? The medication Pemazyre specifically contains the active substance Pemigatinib. How much does pemazyre cost? The pemazyre price in India usually can vary depending on the wholesaler/pharmacy you visit. Pemazyre is available as a brand name drug only, a generic version is not yet available. What is the best price for Pemigatinib? Please contact Toll-free: +91 1800 889 1064 |+919310090915 for pemigatinib price in India. We take the guarantee of quality and delivery anywhere in the world as per the buyer’s requirements. Can I get Pemazyre (Pemigatinib) even if I am not based in India? The Indian Pharma helps patients in accessing or importing Pemazyre (Pemigatinib), not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country.