Spinraza Nusinersen

About Medicine

  • Brand Name: Spinraza
  • Innovator Brand Name: Spinraza
  • API: Nusinersen
  • Packaging: 1 Vial (Per Box)
  • Strength: 12mg/5ml
  • Manufacturer Name: Biogen
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Description

Uses of medication: Nusinersen is used for the treatment of spinal muscular atrophy (SMA) in the adult patient as well as in pediatric. This medication is a survival motor neuron-2 (SMN2) directed antisense oligonucleotide.

Dosage: SPINRAZA (nusinersen) injection comes as the strength of 12 mg/5 mL (2.4 mg/mL). The recommended dose of spinraza should be administered intrathecally. This drug is given in four loading doses; the first three loading doses are given within 14 days; however, the 4th loading dose is given after the 30 days of the 3rd loading dose. The maintenance spinraza dose needs to be administered once every 4-months thereafter.

Treatment Reactions: The most commonly reported nusinersen side effects may include constipation, upper respiratory infection and lower respiratory infection.

Warnings and precautions

  • In patients taking spinraza treatment, renal toxicity, including potentially fatal glomerulonephritis may occur.
  • Excessive use of spinraza sma may lead to renal toxicity which can be spotted by urine protein testing.
  • The nusinersen (spinraza) 12 mg/5 ml is not recommended during pregnancy or breastfeeding as it can affect the baby.
  • Prior to each spinraza dose, patients should be monitored for the platelet count, activated partial thromboplastin time and quantitative spot urine protein testing.

More Info.

Storage: The spinraza injection is a real color solution that is available in a single dose glass vial. This injection is recommended to be stored in refrigerator temperature ranging from 2°C to 8°C (36°F to 46°F). Do not place the spinraza 12 mg/5 ml vial in direct sunlight or the freezer.


Availability in India: The Indian Pharma (TIP) helps connect buyers with suppliers who can ship SPINRAZA at the global level as per the need of buyers. The Indian Pharma provides the guarantee of quality as well as delivery for the SPINRAZA Injections.


Buying Procedure: In order to buy SPINRAZA, you can contact us at our Toll-free number 1800 889 1064 or on WhatsApp number +919650877511 or an Email to us at info@theindianpharma.com along with your ID Proof, Valid Prescription Letter, and Medical Reports.


Conclusion: Spinraza being a blockbuster drug in the SMA treatment and with pride that it is the only medication approved for adults and Paediatric SMA makes it quite unique. More clinical trials are required in order to prove the safety as well as efficacy of this medication and also to look for the long- term outcomes in the SMA treatment.

Commonly Asked Questions

What does Spinraza contain as an active substance?


The Spinraza specifically contains the active substance Nusinersen.


From which class of drug Nusinersen injection belongs?


The nusinersen injection belongs to a class of drugs named antisense oligonucleotides.


How does Nusinersen act?


As a class of antisense oligonucleotide inhibitors, Nusinersen works in order to increase the amount of a certain protein crucial for the muscles as well as nerves in order to work normally.


How much does spinraza cost?


The nusinersen cost in india may vary depending on the pharmacy you visit. The cost for Spinraza 12 mg/5 mL is around 9,584,640 INR for a supply of 5-milliliters.


Where can I get Nusinersen at the best price?


In order to get the best nusinersen price, always buy this medication from such Pharmaceutical Wholesaler Company which is ISO and WHO-GDP certified.


Can I get Nusinersen (Spinraza) even if I am not based in India?


The Indian Pharma helps patients in accessing or importing Nusinersen (Spinraza), not approved in their home country against the legitimate prescription and in conformity with all local laws and regulations of their home country.