Gemcitabine

Facts of GEMCITABINE

  • Brand Name- SHILGEM 200 MG
  • Innovator Brand Name- Gemzar
  • API- Gemcitabine
  • Packaging- Single Vial
  • Strength- 1 G|200 mg
  • Manufacturer Name- Shilpa Medicare
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Description

What is Gemcitabine and what it is used for:

Gemcitabine belongs to a nucleoside metabolic innovator class drug that is generally used in the combination with carboplatin for the treatment of advanced ovarian cancer in a patient who has received at least one prior platinum-based therapy. This drug is also used in the treatment of metastatic breast cancer when combined with paclitaxel and non-small-cell lung cancer in combination with cisplatin. As a single agent gemcitabine is recommended for treating pancreatic cancer.

Dosage: This drug is available in injection form of different concentrations used in the treatment of ovarian cancer breast cancer non-small cell lung cancer and pancreatic cancer.

  • Ovarian Cancer: The recommended dosage of gemcitabine is 1000 mg/m2 should be given intravenously over the 30 minutes on Days 1 and 8 of each 21-day cycle in combination with carboplatin AUC 4 administered intravenously on Day 1 after the administration of gemcitabine.
  • Breast Cancer: The recommended dosage of this drug is 1250 mg/m2 intravenously over 30 minutes on Days 1 and 8 of each 21-day cycle in combination with paclitaxel 175 mg/m2 administered as a 3-hour intravenous infusion on Day 1 before the administration of gemcitabine injection.
  • NSCLC: The recommended dose of gemcitabine is 1000 mg/m2, which should be given intravenously over the 30 minutes on Days 1, 8, and 15 of each one month cycle together with the cisplatin 100 mg/m2 administered intravenously on Day 1’st after the administration of gemcitabine injection. Pancreatic Cancer: The recommended dose for pancreatic cancer is 1000 mg/m2, which should be recommended intravenously over the 30 minutes.

Treatment Reactions: The most common side effects of gemcitabine are given as follows:

  • Peripheral edema
  • Vomiting
  • Hepatic transaminitis
  • Anemia
  • Fever
  • Increased alkaline phosphatase
  • Dyspnea
  • Thrombocytopenia

FAQs

Does Gemcitabine Cause Hair Loss?


Normally gemcitabine does not cause hair loss however patients may experience hair loss in a few cases.


What is the Treatment Cycle of Gemcitabine?


This drug is generally given for approximately four weeks.


Is Gemcitabine a Strong Chemotherapy Drug?


Gemcitabine is a chemotherapy drug used in the treatment of several cancers such as breast cancer, non-small cell lung cancer, ovarian cancer, and pancreatic cancer.


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