polivy polatuzumab vedotin-piiq

  • Brand Name: Polivy
  • Innovator Brand Name: Polivy
  • API: Polatuzumab Vedotin-piiq
  • Dosage Form: 1 Vial (Per Box)
  • Strength: 30/140mg
  • Manufacturer Name: Genentech and Roche
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Description

Polivy Injection Uses

Polivy (Polatuzumab Vedotin-piiq) is a CD79b-directed antibody drug conjugate used in combination with medications bendamustine and a rituximab for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma, not otherwise specified, following at least two prior therapies.

Dosage: The recommended dose of Polivy is 1.8 mg/kg as an intravenous infusion over 90 minutes every 21 days for 6 cycles along with bendamustine and a rituximab. Subsequent infusions may be administered over 30 minutes in case the previous infusion is tolerated. Premedicate with an antihistamine and antipyretic before polatuzumab vedotin. If a planned polivy dose is missed, administer as soon as possible. Adjust the schedule of administration to maintain a 21-day interval between doses.

Side Effects: The most commonly reported polatuzumab vedotin side effects include:

  • Neutropenia
  • Thrombocytopenia
  • Anemia
  • Peripheral neuropathy
  • Fatigue
  • Diarrhea
  • Pyrexia
  • Decreased appetite
  • Pneumonia

Warnings and Precautions:

  • Monitor patients with polatuzumab vedotin for infusion-related reactions during the infusion and for a minimum of 90 minutes after the initial dose.
  • Administer an antipyretic and antihistamine prior to the use of polivy, and monitor patients closely throughout the infusion.
  • Monitor patients with polivy uses for signs of peripheral neuropathy such as hyperesthesia, hypoesthesia, gait disturbance, paresthesia, dysesthesia, neuropathic pain, burning sensation, or weakness.
  • Patients with polatuzumab vedotin 140 mg injection should be monitored for complete blood counts throughout treatment.
  • Females of reproductive potential are advised of the potential risk to a fetus and should contact their healthcare professional if they become pregnant, or if pregnancy is suspected, during therapy with polatuzumab vedotin.
  • Women with polatuzumab vedotin fda label medication are advised to avoid breastfeeding while on polatuzumab vedotin and for at least two months following the last dose.

More info

Storage: Store refrigerated at 2°C to 8°C (36°F to 46°F) in original carton to protect from light. Never use beyond the expiration date printed on the carton. Do not freeze the polivy 30 mg vial. Do not shake. Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship the POLIVY at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality as well as delivery for the POLIVY (polatuzumab vedotin-piiq) for injection. Buying Procedure: In order to buy POLIVY, you can contact us at our Toll-free number 1800 889 1064 or on WhatsApp number +919310090915 or an Email to us at: info@theindianpharma.com along with the legitimate ID Proof, standard Prescription and Medical Reports. Conclusion: Polatuzumab vedotin combined with bendamustine and rituximab resulted in a significantly higher CR rate and decreased the risk of death by 58 percent compared with BR in recipients with transplantation-ineligible Relapsed/Refractory Diffuse Large B-Cell Lymphoma.  

FAQ

What is Polivy? Polivy is an antibody-drug conjugate or ADC mainly designed for treating cancer. The US FDA approved it in June 2019 to treat diffuse large B-cell lymphoma when used along with medications named bendamustine and rituximab. What does Polivy contain as an active substance? The medication Polivy specifically contains the active substance Polatuzumab Vedotin-piiq. How is Polatuzumab Vedotin-piiq supplied? Polatuzumab Vedotin-piiq for injection is a preservative-free, white to grayish-white lyophilized powder, supplied in a single-dose vial. How much does polivy cost? The polivy price in India usually can vary depending on the wholesaler/pharmacy you visit. Polivy is available as a brand name drug only, a generic version is not yet available. What is the best price for Polatuzumab Vedotin-piiq? Please contact Toll-free: +91 1800 889 1064|+919310090915 for polatuzumab vedotin price in India. We take the guarantee of quality and delivery anywhere in the world as per the buyer’s requirements. Can I get Polivy (Polatuzumab Vedotin-piiq) even if I am not based in India? The Indian Pharma helps patients in accessing or importing Polivy (Polatuzumab Vedotin-piiq), not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country.

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