Bortenat (Bortezomib)

Facts of BORTENAT

  • Brand Name: BORTENAT
  • Medicine Name: Bortezomib
  • Company Name: Natco Pharma
  • Supplied as: 2mg as single vial for injection.
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Description

Bortezomib Injection:

Bortezomib is one of the anti-cancer medications used in the treatment of mantle cell lymphoma and multiple myeloma. It is one of the best chemotherapy medication which is injected intravenously. Treatment of multi Myeloma by bortezomib is done in those patients who have not received any treatment previously. Bortezomib in the treatment of multiple Myeloma is combined with other medications to increase its efficiency.

What is Mantle Cell Lymphoma: Mantle cell lymphoma is a type of rare B cell defect. In this type of disease, the abnormal cell produces abnormal antibodies that accumulate at the lymph nodes. There are several chemotherapy medications used in the treatment of Mantle cell lymphoma but the most effective is the use of bortezomib in combination with other medications. It is used in that patient who has at least one prior treatment of chemotherapy.

What is BORTENAT ™?

BORTENAT is indicated for:

  • Treatment of patients with multiple myeloma
  • Treatment of patients with mantle cell lymphoma

Is Bortezomib Chemotherapy Drug:

Bortezomib is one of the best chemotherapy medications according to the Food and Drug Administration used in the treatment of Multiple Myeloma and mantle cell lymphoma. Bortezomib belongs to the proteasome inhibitor class drug that works by inhibiting or slowing the proteasome activity of the lymphoma cells. The effect of bortezomib is positive in the case of a patient suffering from renal impairment and diabetes.

Bortezomib injection Uses:

Bortezomib Injection is used in the treatment of several kinds of cancer such as multiple myeloma and mantle cell lymphoma. It works by stopping or slowing down the growth of the cancerous cell. Bortezomib FDA label Injection is used in the treatment of multiple Myeloma when the patient does not have any prior therapy whereas in the case of Mantle cell lymphoma bortezomib injection is used when the patient has at least one prior therapy.

General Warning: Bortezomib injection in high doses can cause peripheral neuropathy damage.The adverse effect of bortezomib can weaken immunity.

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Bortezomib Side Effect:


The common side effect of bortezomib injection are:


  • Peripheral neuropathy

  • Diarrhea

  • Nausea

  • Vomiting

  • Thrombocytopenia

  • Psychiatric disorder

  • Anorexia condition

  • Loss of appetite

  • Neuralgia

  • Neutropenia

  • Leukopenia

  • Anemia

  • Low platelet count

  • Severe peripheral neuropathy

How Bortezomib Work?


Bortezomib works as a targeted therapy inhibiting the proteasome enzyme complex. The proteasome is the part of the cellular mechanism that performs several functions such as controlling the level of protein as well as helping in cell survival and cell division. With the interference in the activity of the proteasome, the cell can direct to apoptosis (cell suicide).
In several studies, it is found that the cancerous cell is more vulnerable to the effect of proteasome inhibitor as compared to normal cells.


Bortezomib Cost: Bortezomib is a cost-friendly and economical medication. The customer can buy bortezomib injection from any registered pharmaceutical company at an affordable price.


Dosage: The single vial bortezomib contains 3.5mg of bortezomib. The recommended dose of bortezomib is 1.3mg/m2 administered as a 3-5 second bolus intravenous injection. The strength of the dosage should be adjusted so that it overdoses does not cause any adverse effects.


Precautions:


  • Before starting the therapy of the bortezomib doctor should know all the medication that the patient is already taking.

  • The use of Aspirin or products containing Aspirin should be avoided.

  • Special care should be taken in case of pregnancy. Bortezomib can cause fetal damage.

  • If possible pregnancy should be provided while taking bortezomib.

  • Do not breastfeed while taking bortezomib.

Interaction: Several drug interactions are mentioned below:


  • CYP3A4 Inhibitors: if the patient is having bortezomib toxicity then the bortezomib dose is reduced and is used in the combination with a strong CYP3A4 inhibitor such as ritonavir or ketoconazole.

  • Dexamethasone: The administration of bortezomib with dexamethasone is not fully successful.

  • Melphalan-Prednisone: interaction of the struggle with bortezomib is still under study.

Overdose: There is no antidote of bortezomib in humans. The overdose of bortezomib can cause fatalities. According to recent studies the recommended dose can be twice and thus cause malignancy with the development of acute onset of symptomatic hypotension.
If a patient takes Overdose then the for the sign and symptom of the patient should be monitored.


Missed Dose: Immediately recommended to the doctor or Consultant for your missed dose. Taking the missed dose at another time the main cause of overdose toxicity.

Availability

Where can I Buy BORTENAT?


The Indian Pharma connects buyer with the supplier who can ship BORTENAT to any country of the world as per the buyer’s requirement and Government regulations of the country. BORTENAT is manufactured by Natco Pharma.


The Indian Pharma provides options of choosing exporter and supplier of cancer treatment medicines. We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.


Send your inquiry to find Bortenat (Bortezomib) in UAE Iraq, Iran, Saudi Arabia, Jordan, Mexico, Argentina, Brazil, Chile, Colombia, Peru, Venezuela, Romania, Switzerland, Georgia, Turkey, Italy, UK, Ukraine, Azerbaijan, Latvia, Poland, Slovakia, Armenia, Kazakhstan, Moldova, Tajikistan, Turkmenistan, Uzbekistan, Mongolia, Algeria, Mauritius, Uganda, Zimbabwe. Australia and New Zealand. China, Cambodia, Indonesia, Malaysia, the Philippines, Singapore, Thailand, Vietnam, Hong Kong.


Conclusion: Bortezomib injection is one of the best chemotherapy medications used in the treatment of Multiple Myeloma and mantle cell lymphoma. It is one of the safest drugs which causes minimum overdose toxicity.

Commonly asked questions

Is BORTENAT available in India?


BORTENAT is a (prescription drug, prescription medication or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.


Is multiple myeloma a fatal disease?


As multiple myeloma is not a curable disease however it can be dominant in patients for a longer duration of time and thus the patient gets sufficient time to control its effect.


How much does a Velcade short cost?


Velcade is an inexpensive and cheap drug
This is generally available at all registered pharmaceutical companies. Velcade can also be bought online by placing an order on the company’s official website if the company is providing worldwide shipping.


You can access medicine in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc.)


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BORTENAT can be made available in Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalo