- Veenat availability
- Different brands of Imatinib Mesylate
- Imatinib Mesylate supplier/Exporters / Distributor / Wholesaler
Uses of Imatinib:
Veenat contains imatinib and is a famous medicine called protein tyrosine kinase inhibitor. This medication is used to treat cancer. Specifically, it is used for chronic myelogenous leukemia treatment (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome.
List of substitutes for Veenat 400 mg Tablet
- Altanib 400 mg Tablet (Alkem Laboratories Ltd.)
- Cadinib 400 mg Tablet (Cadila Pharmaceuticals Ltd.)
- Mitinab 400 mg Tablet (Glenmark Pharmaceuticals Ltd.)
How long is Imatinib taken?
Treatment should be continued as long as the patient continues to benefit.
How Does Imatinib Works?
Imatinib (Veenat) is a specific protein-tyrosine kinase inhibitor (TKI) which mainly works by inhibiting the bcr-abl (a tyrosine kinase), the constitutive abnormal tyrosine kinase formed by the Philadelphia chromosomes abnormality in the CML. Imatinib basically inhibits the proliferation and it also induces apoptosis in bcr-abl positive cell lines as well as maiden or fresh leukemic cells from the Philadelphia chromosome positive chronic myeloid leukemia. Imatinib also inhibits the colony formation in the assays using ex vivo peripheral blood and also samples of bone marrow from the CML patients.
In the Vivo, imatinib inhibits the growth of tumor of bcr-abl transfected murine myeloid cells as well as bcr-abl positive leukemia lines derived from the CML patients in the blast crisis. It is also an specific inhibitor of the receptor tyrosine kinases for the PDGF (platelet-derived growth factor) and stem cell factor (SCF), c-kit, and inhibits PDGF- and cellular events of SCF-mediated. Moving on vitro, this medication inhibits the proliferation and also induces the apoptosis in the GIST cells, which mainly express an activating c-kit mutation.
What kind of drug is Imatinib?
Imatinib (Veenat generic) is a type of cancer growth blocker called a tyrosine kinase inhibitor (TKI).
Side effects of Imatinib: Certain side effects may occur when you are on this medication. These comprise diarrhoea, change in amount of urine, loss of appetite, dark coloured urine, unusual bleeding, weakness, tiredness, vomiting, etc
Veenat FDA approval: Imatinib was approved for medical use in the United States in 2001. Imatinib cost is quite decent as well as affordable.