Stiripentol

Fact of Medicine
Brand Name: Diacomit
Innovator Brand Name: Diacomit
API: Stiripentol
Packaging: 60 capsules/Powder Packets
Strength: 250/500mg
Manufacturer Name: Biocodex

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Description

Stiripentol Medication

Diacomit (Stiripentol) is an effective and FDA-approved anti-seizure drug originated specifically for the treatment of seizures associated with Dravet syndrome in patients aged two years and older taking clobazam.

Dosage: The dosage of stiripentol is 50 mg per kg daily, administered by mouth in 2/3 divided doses. Reduce stiripentol dose or discontinue gradually. Capsule of stiripentol is swallowed whole with water during a meal. Stiripentol capsules must not be broken/opened. Powder for suspension is mixed in a glass of water and should be administered promptly after mixing during a meal. In the event of a missed dose of stiripentol, it should be administered as soon as possible. If it is almost the time for the next dose of stiripentol, the patients should not administer the missed dose. Doses should not be doubled.

Side Effects: The most commonly reported stiripentol side effects may include:

  • Somnolence
  • Decreased appetite
  • Agitation
  • Ataxia
  • Decreased weight
  • Hypotonia
  • Nausea
  • Tremor
  • Dysarthria
  • Insomnia

Warnings and Precautions:

  • Patients should be monitored for the somnolence, mainly when stiripentol capsules are used concomitantly with other CNS depressants or clobazam.
  • Diacomit may cause decreases in weight and appetite. Growth as well as weight of pediatric patients treated with diacomit 250 mg must be precisely monitored.
  • Diacomit may cause a bit decline in neutrophil and platelet counts. The hematologic testing is obtained before initiating therapy with diacomit 500 mg and then every six months.
  • As with maximum AEDs (antiepileptic drugs, the stiripentol use is gradually withdrawn for minimizing the risk of increased seizure frequency and status epilepticus.
  • Patients are advised to inform their healthcare practitioner if they become pregnant or intend to become pregnant while on stiripentol dosage.
  • Patients are instructed to notify their doctor if they are breast feeding or intend to breastfeed during stiripentol therapy.

More info

Storage: Store Diacomit (Stiripentol) in a dry place at temperature 20°C-25°C (68°F-77°F); excursions permitted to 15°C-30°C (59°F-86°F). Store the capsules or powder for suspension in the original package in order to protect from light. Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship DIACOMIT at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality as well as delivery for the DIACOMIT Capsules or Powder for suspension. Buying Procedure: In order to buy DIACOMIT, you can contact us at our Toll-free number 1800 889 1064 or on WhatsApp number +919310090915 or an Email to us at: info@theindianpharma.com along with your Identity Proof, Legitimate Prescription and Medical Reports. Conclusion: Diacomit (Stiripentol) is the first antiepileptic agent to have clinically shown the efficacy in Dravet syndrome in 2 multicenter, double-blind, placebo-controlled, randomized trials. In these trials, recipients with Dravet syndrome noticed significantly fewer seizures with the therapy of stiripentol in comparison to placebo.

FAQ

What is Diacomit? Diacomit capsules for oral use or powder for oral suspension are used to treat seizures associated with Dravet syndrome in patients aged 2 years and older with clobazam. How is Stiripentol supplied? Stiripentol is supplied in 2 convenient dosing forms: capsules and powder for oral suspension (fruit-flavored powder packets to be mixed in water). The capsules are available in two different strengths as:
  • stiripentol 250 mg
  • stiripentol 500 mg
What does Diacomit contain as an active substance? The medication Diacomit specifically contains the active substance Stiripentol. Is Stiripentol an FDA approved drug? Yes, Stiripentol is an FDA approved drug. How much does diacomit cost? The diacomit price in India usually may vary depending on the wholesaler/pharmacy you visit and of course the brand you choose. What is the best price of Stiripentol? Please contact Toll-free: +91 1800 889 1064|+919310090915 for stiripentol price in India. We take guarantee of quality as well as delivery anywhere in the world as per the buyer’s requirements. Can I get Diacomit (Stiripentol) even if I am not based in India? The Indian Pharma helps patients in accessing or importing Diacomit (Stiripentol), not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country.

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