What is Leuprolide acetate and what it is used for:
It is a Gonadotropin-releasing hormone (GnRH) used to treat advanced prostatic cancer.
Leuprolide acetate injection is also used to treat children suffering from Central precocious puberty, which means attaining puberty at a very early age. This injection is also combined with other medications for the treatment of endometriosis (it is a condition in which the tissue lining uterus grows to other parts of the body and causes pain) and anemia.
This drug is administered directly into the subcutaneous region. It is not prescribed for intravenous injection. The active ingredient leuprolide acetate is mixed with sodium chloride, which works as a tonicity adjuster, water for injection, and Benzyl alcohol as a preservative.
Some common side effects of this drug include hot flashes, pain, edema, GI disorders, respiratory disorder, urinary disorder, injection site reactions, joint disorders, testicular atrophy, flu syndrome, asthenia, and skin reaction.
Warning and Precautions:
- Increased risk of Hyperglycemia and Diabetes has been reported in a patient with prostate cancer.
- Increased risk of myocardial infarction has been reported when GnRH analog is used.
- Effect on QT/QTc Interval has been seen.
- Some patients report having convolutions after the leuprorelin acetate.
- The level of prostate-specific antigen and serum testosterone is monitored.
- People having allergies to benzyl alcohol should not take this drug.