General Warning: Axitinib can cause bleeding which can be serious. Call your doctor right away or seek medical help if you develop signs or symptoms of unexpected bleeding or bleeding that lasts a long time such as unusual bleeding from the gums, red or black stools, menstrual bleeding or vaginal bleeding, pink or brown urine and cough up blood or blood clots.
Axitinib belongs to targeted therapy. It is a receptor protein kinase inhibitor and prescription medication recommended in order to treat advanced kidney cancer (advanced renal cell carcinoma or RCC) when one prior drug treatment regimen for your RCC has not worked.
Axitinib side effects:
The most common side effects of axitinib tablets are reported as follows:
- diarrhea (frequent or loose bowel movements)
- Tiredness or feeling weak
- decreased appetite
- decreased weight
Dosage: The initial dose is axitinib 5 mg orally twice daily. Dose adjustments should be made on behalf of individual safety as well as tolerability. Administer axitinib dose about 12 hours apart with or without food. The axitinib should be swallowed whole with the glass of water.
- Your healthcare professional should check your urine for protein prior to and during your treatment with the axitinib 1mg.
- Avoid drinking grapefruit juice or eat grapefruit. Grapefruit can be responsible for increasing the amount of this drug in your blood.
- Effective birth control should be used during treatment and for at least 7 days after your last dose of axitinib.
- If your female partner becomes pregnant during your treatment with the axitinib, inform your doctor right away.
- This medication shouldn’t be recommended if you are breastfeeding or plan to breastfeed.
- Prior to initiating treatment with this dug, female patients should tell their healthcare provider if they are pregnant or plan to become pregnant.
- If you are carrying a plan to have surgery or have had a recent surgery. You must stop consuming this drug for at least 2 days prior to planned surgery.