Trodelvy (Sacituzumab govitecan-hziy)

Brand Name: Trodelvy
Innovator Brand Name: Trodelvy
API: Sacituzumab govitecan-hziy
Packaging: 1 Vial (Per Box)
Strength: 180mg lyophilized powder for injection
Manufacturer Name: Gilead Sciences, Inc.

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Uses of medication:

Trodelvy (Sacituzumab govitecan-hziy) is a Trop-2-directed ADC and topoisomerase inhibitor conjugate approved to treat adults with:

  • Unresectable locally advanced or mTNBC (metastatic triple-negative breast cancer) who have previously been treated with two or more systemic therapies, at least one of them for metastatic disease.
  • Unresectable locally advanced or metastatic hormone receptor (HR)- positive, human epidermal growth factor receptor 2 (HER2)-negative (IHC 0, IHC 1+ or IHC 2+/ISH–) breast cancer who have been treated with endocrine-based therapy and at least two additional systemic therapies in the metastatic setting.
  • Locally advanced or metastatic urothelial cancer (mUC) who have previously been treated with platinum-containing chemo and either PD-1 (which stands for programmed death receptor-1) or PDL1 (which stands for programmed death-ligand 1 inhibitor).

Dosage: The recommended dose of Trodelvy (Sacituzumab govitecan-hziy) injection is 10 mg/kg given as an IV infusion once a week on Days 1 & 8 of 21-day therapy cycles until disease progression or in case of unacceptable toxicity. Do not administer doses of Trodelvy more than 10 mg per kg. Trodelvy needs to be administered as an intravenous (IV) infusion only. Avoid administering as an intravenous (IV) push or bolus.

First infusion: Administer intravenous (IV) infusion over three hours. Observe patients throughout the infusion and for at least 30 minutes after the initial dose in order to notice/see any sign or symptom of infusion-related reactions.

Subsequent infusions: Administer intravenous (IV) infusion over 1 to 2 hours if previous infusions were tolerated. Observe patients throughout the IV infusion and for at least 30 minutes following the IV infusion.

Treatment Reactions: The most commonly reported side effects of Trodelvy 180 mg injection are:

  • decreased white blood cell
  • decreased red blood cell counts
  • feeling tired or weak
  • hair loss
  • constipation
  • increased sugar levels in the blood
  • decreased protein levels (albumin) in the blood
  • decreased appetite
  • changes in kidney function test
  • increased levels of alkaline phosphatase enzyme in the blood (test for liver or bone problems)
  • reduced levels of sodium, potassium, and magnesium in the blood.

Warnings and Precautions:

  • Prior to Trodelvy 180 mg therapy, pre-medicate patients prevent infusion reactions and prevent chemo-induced nausea and vomiting (CINV). Premedicate with H1/H2 blockers, antipyretics prior to IV infusion, and use corticosteroids in all those with a history of infusion reactions.
  • Severe, deadly, or fatal neutropenia may occur in those treated with Trodelvy. Withhold Trodelvy treatment for absolute neutrophil count (ANC) less than 1500/mm3 on Day 1 of any treatment cycle or neutrophil count less than 1000/mm3 on Day 8 of any cycle. Modifications in Trodelvy doses may be needed because of neutropenia.
  • Trodelvy 200 mg treatment can cause serious diarrhea. If diarrhea occurs, evaluate for infectious causes and if negative, quickly start loperamide, 4 mg at the beginning followed by 2 mg with every episode of diarrhea for a maximum of 16 mg daily. Discontinue loperamide twelve hours after the diarrhea resolves.
  • Critical hypersensitivity reactions including deadly anaphylactic reactions may occur in patients treated with Trodelvy. Closely assess patients for infusion-related and hypersensitivity reactions during each infusion and for at least 30 minutes after each infusion.
  • Trodelvy 200 mg is emetogenic. It may cause nausea and vomiting. Additional antiemetics as well as other supportive measures may also be considered as clinically required. Patients should be given take-home drugs with clear words to prevent and treat nausea and vomiting.

More info

Storage:  Store vials of Trodelvy in a refrigerator at 2 to 8°C (36 to 46°F) in the original carton to protect them from the light until the time of reconstitution. It is not advisable to freeze this medicine.

Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship TRODELVY® at the global level as per the requirement of buyers. The Indian Pharma provides a guarantee of quality and delivery for the TRODELVY® (sacituzumab govitecan-hziy) injection.

Buying Procedure: In order to buy Trodelvy injection online, you can contact us at our Toll-free Number 1800 889 1064 or on WhatsApp Number +919310090915 or Email us at: along with your Identity Proof, Valid Prescription Letter, and Medical Reports.

Conclusions: Trodelvy is a novel targeted treatment with promising activity in urothelial cancer (mUC), HR+/HER2- metastatic breast cancer, and triple-negative breast cancer (TNBC), which is an aggressive form of breast cancer, that may improve outcomes for those whose cancer did not respond to previous therapy and who have limited therapeutic options.


What does Trodelvy contain as an active substance?

Trodelvy specifically contains the active substance Sacituzumab govitecan-hziy.

How is Trodelvy supplied?

Trodelvy is supplied for injection: 180 mg lyophilized powder in a single-dose vial for intravenous use. It is available by prescription only.

How much does Trodelvy cost in India?

Get the best Trodelvy cost in India. If you want to buy it online, then THE INDIAN PHARMA (TIP) can help you to access this medicinal product at the most competitive price in India through legal channels.

Is the Trodelvy Injection Available In India?

Trodelvy is an imported medicine that is not readily available in India. It can be imported against a valid prescription and import permit. THE INDIAN PHARMA (TIP) can facilitate the supply of Trodelvy 180 mg after fulfilling the legal requirement (if applicable). Please contact us via +919310090915 or TOLL-FREE: 1800-889-1064 or write to us at to buy Trodelvy in India.

Can I get Trodelvy even if I am not based in India?

THE INDIAN PHARMA (TIP) helps patients in accessing/import Trodelvy (Sacituzumab govitecan-hziy), not approved in their home country against the valid prescription and in conformity with the local laws and regulations of their respective country.

Where can I get Trodelvy at the best price?

In order to get the best Trodelvy injection price in India and other countries, always buy this medication from a Pharmaceutical Wholesaler Company which is GDP certified. Noida-based THE INDIAN PHARMA (TIP) can offer the best price for Trodelvy (Sacituzumab govitecan-hziy).

Is it safe to buy Trodelvy online in India?

Yes, one can buy Trodelvy from India-based The Indian Pharma (TIP) if Trodelvy 180 mg is not registered or is unavailable in the country. We can facilitate the supply of Trodelvy injection through legal channels.