Trodelvy (Sacituzumab govitecan-hziy)

Brand Name: Trodelvy
Innovator Brand Name: Trodelvy
API: Sacituzumab govitecan-hziy
Dosage Form: 1 Vial (Per Box)
Strength: 180mg
Manufacturer Name: Gilead Sciences, Inc.

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Description

Trodelvy Uses

Trodelvy (Sacituzumab govitecan-hziy) is a Trop-2-directed antibody and topoisomerase inhibitor conjugate used for the treatment of adult patients with metastatic triple-negative breast cancer (mTNBC) who have received at least two prior therapies for metastatic disease.

Dosage: The recommended dose of Trodelvy is 10 mg/kg, which should be administered as an intravenous infusion once weekly on Days 1 and 8 of 21-day treatment cycles. Continue treatment until the disease is progressive or unacceptable toxicity occurs. Avoid administering this medication at doses higher than 10 mg/kg. Administer it as an intravenous infusion only. Do not administer as an intravenous push or bolus.

Side Effects: The most commonly reported trodelvy side effects (incidence >25%) include:

  • nausea
  • neutropenia
  • diarrhea
  • fatigue
  • anemia
  • vomiting
  • alopecia
  • constipation
  • rash
  • decreased appetite
  • abdominal pain

Warnings and Precautions:

  • Use of trodelvy breast cancer drug is restricted in patients who have experienced a severe hypersensitivity reaction to this medication.
  • Observe patients closely for infusion-related reactions during each trodelvy 180 mg infusion and for at least 30 minutes after completion of each infusion.
  • The respective patients who are on Sacituzumab govitecan-hziy injection treatment and with reduced UGT1A1 activity should be monitored for severe neutropenia.
  • The mechanism of action suggests that trodelvy drug can be responsible for causing teratogenicity and/or embryo-fetal lethality when administered to a pregnant woman.
  • Women should not breastfeed during treatment and for one month following the last trodelvy dose.
  • Patients at risk of neutropenia must immediately contact their health specialist if they experience fever, chills, or other signs of infection

More info

Storage: Store trodelvy 180 mg vial in a refrigerator at 2°C to 8°C (36°F to 46°F) in the original carton to protect from the light until time of reconstitution. Do not freeze.

Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship the TRODELVY at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality as well as delivery for the TRODELVY Injections.

Buying Procedure: In order to buy TRODELVY, you can contact us at our TOLL-FREE Number: 1800 889 1064 or on WhatsApp number +919650877511 or an Email to us at: info@theindianpharma.com along with the legitimate ID Proof, Standard Prescription and Medical Reports.

Conclusions: Sacituzumab govitecan is a novel targeted treatment with promising activity in Triple-Negative Breast Cancer, which is an aggressive form of breast cancer, that may improve outcomes for patients whose cancer did not respond to previous treatment and who have limited treatment options

FAQ

What is Trodelvy?
Trodelvy is a prescription medication used to treat adult patients with:
triple-negative breast cancer (negative for estrogen and progesterone hormone receptors and HER2) that has spread to other parts of the body (metastatic) or cannot be eliminated by surgery, and who have received 2 or more prior therapies, including at least one therapy for metastatic disease.
bladder cancer and cancers of the urinary tract that have spread or cannot be eliminated by surgery, and who have received a platinum-containing chemotherapy medication and also received an immunotherapy medication.

When was Trodelvy FDA approved?
In April 2020, Trodelvy was approved by the US Food and Drug Administration..

What does Trodelvy contain as an active substance?
The medication Trodelvy specifically contains the active substance Sacituzumab govitecan-hziy.

How much does trodelvy cost?
The trodelvy price in India usually can vary depending on the wholesaler/pharmacy you visit. Trodelvy is available as a brand name drug only, a generic version is not yet available.

What is the best price for Sacituzumab govitecan?
Please contact Toll-free: +91 1800 889 1064 |+919650877511 for sacituzumab govitecan price in India. We take the guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.

Can I get Trodelvy (Sacituzumab govitecan-hziy) even if I am not based in India?
The Indian Pharma helps patients in accessing or importing Trodelvy (Sacituzumab govitecan-hziy), not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country.

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