Gavreto (Pralsetinib)

  • Brand Name: Gavreto
  • Innovator Brand Name: Gavreto
  • API: Pralsetinib
  • Dosage Form: 60/90/120 Capsules
  • Strength: 100mg
  • Manufacturer Name: Genentech, Inc.
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Description

Gavreto (Pralsetinib) Uses

Gavreto (Pralsetinib) is a kinase inhibitor indicated for the treatment of adult patients with metastatic rearranged during transfection (RET) fusion- positive non-small cell lung cancer (NSCLC).

Dosage: The recommended dose of Pralsetinib is 400 mg administered orally once daily on an empty stomach (no food intake for at least 120 minutes before and at least 60 minutes after taking Pralsetinib). Continue treatment until the disease is progressive or unacceptable toxicity occurs. If a pralsetinib dose is missed, it can be taken as soon as possible on the very same day. Resume the regular daily dose schedule for Pralsetinib the next day. Do not take an additional dose if vomiting occurs after Pralsetinib but continue with the next dose as scheduled.

Side Effects: The most commonly reported pralsetinib side effects (≥25%) include:

  • Fatigue
  • Constipation
  • Hypertension
  • Musculoskeletal pain

Warnings and Precautions:

  • Monitor patients with pralsetinib 100 mg capsules for pulmonary symptoms indicative of ILD/pneumonitis.
  • Optimize blood pressure prior to initiating therapy with Gavreto. Blood pressure should be monitored after 1 week, at least monthly thereafter.
  • Monitor AST and ALT prior to initiating therapy with pralsetinib capsule, every 2 weeks during the first 3 months, then monthly thereafter.
  • Withhold Pralsetinib for at least 5 days prior to elective surgery. Avoid using it for at least 2 weeks after any major surgery and until adequate wound healing.
  • Women should avoid breastfeed during treatment with gavreto 100 mg capsules and for seven days after the final dose. Females should avoid using gavreto during pregnancy. Advise females of reproductive potential to inform their health specialist of a known/suspected pregnancy.

More info

Storage: Store Pralsetinib at 20°C to 25°C (68°F to 77°F); excursions are permitted from 15°C to 30°C (59°F to 86°F). Protect the Pralsetinib Capsules from moisture. Keep Pralsetinib and all drugs out of the reach of children. Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship the GAVRETO at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality as well as delivery for the GAVRETO Capsules. Buying Procedure: In order to buy GAVRETO, you can contact us at our Toll-free number 1800 889 1064 or on WhatsApp number +919310090915 or an Email to us at: info@theindianpharma.com along with the legitimate ID Proof, standard Prescription and Medical Reports. Conclusions: Findings concluded that the drug Pralsetinib is a novel, well-tolerated, promising, once-daily oral treatment option for patients with RET fusion +Ve Non-Small Cell Lung Cancer.

FAQ

What is Gavreto? Gavreto is a targeted therapy introduced to treat metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC), diagnosed by a US FDA-approved test, in adult patients. What does Gavreto contain as an active substance? The medication Gavreto specifically contains the active substance Pralsetinib. How is Pralsetinib supplied? Pralsetinib is supplied as Capsules in 100 mg dose strength for oral administration. How much does gavreto cost? The gavreto price in India usually can vary depending on the wholesaler/pharmacy you visit. Gavreto is available as a brand name drug only, a generic version is not yet available. What is the best price for Pralsetinib? Please contact Toll-free: +91 1800 889 1064|+919310090915 for pralsetinib price in India. We take the guarantee of quality and delivery anywhere in the world as per the buyer’s requirements. Can I get Gavreto (Pralsetinib) even if I am not based in India? The Indian Pharma helps patients in accessing or importing Gavreto (Pralsetinib), not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country.
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