Inotuzumab

Fact of Medicine

  • Brand Name: Besponsa
  • Innovator Brand Name: Besponsa
  • API: Inotuzumab Ozogamicin
  • Packaging: Single-Dose Vial
  • Strength: 0.9 mg lyophilized powder
  • Manufacturer Name: Pfizer
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Description

Inotuzumab Uses:

Inotuzumab is intended for the treatment of adult patients with acute lymphoblastic leukaemia who have previously treated other treatments and for whom those treatments have unsuccessful.

Dosage: This medication always should be used exactly as your healthcare practitioner has told you. Your healthcare provider will determine the appropriate dose and will give you inotuzumab injection through a drip into your vein (intravenous infusion) which will run for one hour. Every inotuzumab dose needs to be administered weekly and each treatment cycle should be for 3 doses.

If you’re not responding to this drug within three cycles, you need to interrupt your treatment.

In an event of a missed or drug overdose, call your healthcare professional team as soon as possible.

Treatment Reactions: The most commonly reported side effects with besponsa may include:

  • Pyrexia
  • Fatigue
  • Nausea
  • Anemia
  • Infection
  • Headache
  • Leukopenia
  • Hemorrhage
  • Neutropenia
  • Abdominal pain
  • Hyperbilirubinemia
  • Febrile neutropenia
  • Thrombocytopenia
  • Transaminases increased

Warnings and Precautions:

  • Patients need to be monitored for the liver tests, including AST, ALT, bilirubin, and alkaline phosphatase, before and after every besponsa dose.
  • Patients must be closely monitored for the toxicities post-HSCT, including the symptoms of infection as well as VOD.
  • Patients need to be monitored for the complete blood counts before each dose of this drug.
  • Patients must be closely monitored during and for minimum one hour following the completion of infusion.
  • The use of inotuzumab ozogamicin injection by pregnant women may be responsible for causing embryo-fetal harm.
  • Respective females must be instructed to avoid breastfeeding while taking treatment with inotuzumab 1 mg and for 2 months following the last dose.
  • Males as well as females must seek instructions about fertility preservation prior to the treatment with inotuzumab 1 mg.

More Info.

Storage: Refrigerate (2-8°C; 36-46°F) inotuzumab ozogamicin vials and store in the original carton in order to protect from light. Avoid freezing this medication.

This is a kind of cytotoxic drug. Applicable handling as well as disposal processes must be imposed.

Availability in India: The Indian Pharma helps to connect buyers with suppliers who can ship BESPONSA across the world as per the need of buyer’s. The Indian Pharma provides guarantee of quality and delivery for the BESPONSA Injections.

Buying Procedure: In order to buy BESPONSA, you can contact us at our Toll-free number 1800 889 1064 or on WhatsApp number +918130290915 or an Email to us at: info@theindianpharma.com.

Conclusion: The existing outcomes concluded that the BESPONSA (inotuzumab ozogamicin) has clinically impactful activity in relapsed/refractory acute lymphoblastic leukaemia. Treatment with this medication have offered improved CR rate as well as MRD negativity rate.

Commonly Asked Questions

What is the active ingredient in BESPONSA?

BESPONSA mainly contains inotuzumab ozogamicin as an active ingredient.

Which group of medicines inotuzumab ozogamicin belongs?

It belongs to a group of medications named antineoplastic agents, that mainly target cancer cells.

How does Besponsa work?

This drug mainly acts in order to attach to cells with CD22 protein. This CD22 protein exists on the cells of lymphoblastic leukaemia. Once attached to cells of the lymphoblastic leukaemia, the drug transmits a substance into the cells that are involved in interfering with the cells’ DNA and kills them.

Who offers the best price for inotuzumab?

To get the best inotuzumab price, go with any pharmaceutical wholesaler company that holds the WHO-GDP & ISO certifications.