Buy Denosumab injection 120 mg Online at Best Price/Cost in India

Denosumab

  • Brand Name: Xgeva
  • API: Denosumab
  • Packaging: Single-dose Vial
  • Strength: Injection: 120 mg/1.7 mL (70 mg/mL)
  • Manufacturer: Dr. Reddy Laboratories Ltd
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Description

Xgeva (Denosumab Injection 120 MG/1.7 mL)

Uses of Medicine: Xgeva (denosumab solution for injection) is used for the prevention of skeletal-related events (such as fractures, spinal cord compression, and the need for radiation or surgery to bone) in patients with bone metastases from solid tumors. It is also used for the treatment of giant cell tumors of bone that are unresectable or where surgical resection is likely to result in severe morbidity. Additionally, this therapeutic drug is used in adults and skeletally mature adolescents for treating hypercalcemia of malignancy refractory to bisphosphonate therapy.

Dosage and Side Effects

Xgeva should only be given via subcutaneous injection and must not be administered intravenously, intramuscularly, or intradermally. For Multiple Myeloma and Bone Metastasis from Solid Tumors, the recommended dosage is 120 mg administered once every 4 weeks through a subcutaneous injection, which can be given in the upper arm, upper thigh, or abdomen. For patients with a Giant Cell Tumor of Bone, the suggested dosing regimen is 120 mg administered subcutaneously every 4 weeks. Additionally, in the first month of therapy, 120 mg doses should be given on Days 8 and 15. In conjunction with this treatment, ensure that calcium and vitamin D are provided as needed to manage or prevent hypocalcemia. For Hypercalcemia of Malignancy, the recommended treatment is 120 mg administered every 4 weeks with additional 120 mg doses given on Days 8 and 15 of the first month. The injection should be administered subcutaneously in the upper arm, upper thigh, or abdomen.

The most common side effects of Denosumab injection are fatigue, bone pain, nausea, and low calcium levels. Some may experience joint pain, headache, or increased risk of jaw bone problems (osteonecrosis).

Warning and Precautions

  • Xgeva contains denosumab, which is also present in Prolia, a therapeutic drug used for different indications. Concurrent use of Xgeva and Prolia is not recommended as it may result in additive pharmacological effects, increasing the risk of adverse reactions.
  • Severe hypersensitivity reactions, including anaphylaxis, have been reported with Denosumab 120 mg/1.7 mL (70 mg/mL) injection. Patients should be monitored closely during and after the administration. In the event of a hypersensitivity reaction, discontinue it immediately and start appropriate treatment.
  • Treatment with Denosumab 120 mg/1.7 mL injection can cause severe hypocalcemia, which can be life-threatening if not properly managed. Patients with pre-existing hypocalcemia must correct their calcium levels before starting treatment. Regular monitoring of calcium levels is advised, especially in patients with renal impairment or those predisposed to hypocalcemia.
  • Osteonecrosis of the Jaw (ONJ) has been reported in patients receiving this therapeutic drug, particularly in those undergoing invasive dental procedures. Patients should maintain good oral hygiene and have a dental examination before starting therapy.
  • During treatment, avoid invasive dental procedures if possible. Discontinuation of Denosumab treatment has been associated with an increased risk of MVF. Patients should be assessed for the risk of vertebral fractures, and alternative therapies should be considered to mitigate this risk after stopping this treatment.
  • Denosumab injection may cause fetal harm when administered to pregnant women. Women of reproductive potential should use effective contraception during treatment and for at least 5 months after the last dose. If pregnancy occurs, the patient should be informed of the potential risks to the fetus.

FAQ's

What is the active substance in Xgeva?

Denosumab is the active substance in Xgeva.

How is Denosumab supplied?

This therapeutic drug is supplied for Injection: 120 mg/1.7 mL (70 mg/mL) solution in a single-dose vial for subcutaneous use only.

Who has introduced the generic version of Denosumab in India?

Dr. Reddy Laboratories Ltd has introduced a generic version of Denosumab in India under the brand Xgeva.

How much does Denosumab cost?

Please Call/WhatsApp: +91 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 to know the exact Denosumab cost in India. If you want to buy Denosumab online, then THE INDIAN PHARMA (TIP) can help you access this medicinal product at the most competitive price through legal channels.

Is Denosumab available in India?

Denosumab is a pharmaceutical prescription medicinal product that can only be dispensed against a valid prescription from a treating physician. THE INDIAN PHARMA (TIP) can facilitate the supply of this drug to all locations after fulfilling the legal requirements (if applicable). Please contact us at +91 8130290915 | TOLL-FREE: 1800-889-1064 or at info@theindianpharma.com to buy Denosumab from India at the best price.

Can I get Denosumab injections even if I am not based in India?

THE INDIAN PHARMA (TIP) helps patients access Denosumab, which is not approved in their home country, against a valid prescription and in conformity with their respective country’s local laws and regulations. Send your inquiry to find generic Denosumab in UAE, Iraq, Iran, Argentina, Brazil, Chile, Colombia, Peru, Saudi Arabia, Jordan, Mexico, Venezuela, Romania, Switzerland, Georgia, Turkey, Italy, UK, Ukraine, Sri Lanka, Afghanistan, Poland, Slovakia, Armenia, Kazakhstan, Germany, Azerbaijan, Latvia, Moldova, the Philippines, Tajikistan, Turkmenistan, Uzbekistan, Mongolia, Algeria, Mauritius, Uganda, Zimbabwe, Australia, New Zealand, China, Cambodia, Indonesia, Malaysia, Singapore, Thailand, Vietnam, Kenya, Morocco, Hong Kong.

Where can I get the best Denosumab Cost Price in India?

The price of Denosumab is low and reasonable in India compared to other countries. If you wish to buy Denosumab injections online from India at an affordable price, contact us today. We will help facilitate the supply of this therapeutic drug at the lowest possible prices.

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Yes, one can buy generic Denosumab online at the best price from THE INDIAN PHARMA (TIP) if this drug is not registered or is unavailable in their country. TIP can help facilitate the supply/export of Denosumab injections through legal channels.

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