Ipilimumab Injection

Fact of Medicine

  • Innovator Brand Name: Yervoy
  • API: Ipilimumab
  • Strength: Ipilimumab 50mg/10ml

Description

Uses of Ipilimumab:

Ipilimumab is a monoclonal antibody medication is used:

  • In order to treat a type of skin cancer called melanoma.
  • In people with kidney cancer (renal cell carcinoma) together with the nivolumab.

The medication is undergoing clinical trials for the treatment of non-small cell lung carcinoma (NSCLC), small cell lung cancer (SCLC), bladder cancer and metastatic hormone-refractory prostate cancer.

Dosage: Ipilimumab injection alone is given to you into your vein through an intravenous (IV) line over 90 minutes.

When Ipilimumab is used together with the nivolumab, nivolumab is given to you into your vein through an IV line over 30 minutes. Then Ipilimumab is also given through an IV over 30 minutes on the same day.

Ipilimumab together with nivolumab is usually recommended every 3 weeks for 4 doses. After that, the drug nivolumab is usually given alone every two or four weeks.

In case of drug overdose, immediately call your healthcare provider.

Treatment Reactions:

The most commonly reported ipilimumab side effects include:

  • fatigue
  • diarrhea
  • pruritus
  • rash
  • colitis
  • nausea
  • vomiting
  • headache
  • weight loss
  • pyrexia
  • insomnia
  • decreased appetite

Warnings and Precautions:

  • Patients should be monitored due to an increased risk of gastrointestinal bleeding if they are taking anticoagulants with ipilimumab.
  • Breastfeeding should be discontinued during the treatment with yervoy.
  • The liver function tests should be evaluated prior to each ipilimumab dosage.
  • Clinical chemistries, ACTH level, and thyroid function tests should be monitored prior to each dose.
  • Blood tests should be performed prior to starting and during treatment with Ipilimumab injection.
  • Inform your doctor prior to use of Ipilimumab 50 mg/10 ml if you have had an organ transplant or have liver problems.
  • Females with childbearing potential should avoid becoming pregnant while on Ipilimumab 50 mg/10 ml medicine.

More Info.

Storage: Store Ipilimumab injection under refrigeration at 2°C to 8°C (36°F to 46°F). Protect this medicine from light by storing in the original carton until time of use. Do not freeze or shake.

Buying Procedure: In order to buy IPILIMUMAB, you just need to contact us at our Toll-free number +91 1800 889 1064 (8130290915) or Email–info@theindianpharma.com

Conclusion: The drug Ipilimumab mainly is a first-in-class T-cell potentiator that has shown a significant activity against the stage IV melanoma with durable remissions in the multiple phase 2 trials and has demonstrated a quite significant survival advantage in phase 3 randomized trial.

Concurrent combinational therapy with the nivolumab and ipilimumab had a manageable safety profile.

Commonly Asked Questions

How does Ipilimumab work? 

This medication works to activate the immune system by targeting CTLA-4, a protein receptor that downregulates the immune system.

When Ipilimumab was approved for medical use? 

In March 2011, the Ipilimumab was approved by the US Food and Drug Administration.

What is the cost of Ipilimumab? 

The ipilimumab cost is quite reasonable in India. You must buy this drug from a WHO-GDP & ISO certified pharmaceutical wholesaler company.

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