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Pemetrexed 500 MG/100 MG Injection

Facts of PEMETREXED INJECTION

  • API: Pemetrexed
  • Packaging & Strength: 1 Vial(s) Of 100 mg and 500 mg
  • Form : Vial
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Description

Uses of Medicine: 

Pemetrexed 500 MG/100 MG injection is a folate analog metabolic inhibitor. It is supplied generically as well as as brand name medicine. Patients, Healthcare Professionals (HCPs), or Hospitals can buy Pemetrexed 100 mg/500 mg injection vials online from India through THE INDIAN PHARMA (a trusted Pemetrexed Supplier, Exporter, and Contract Manufacturer in India) for the management and treatment of:
  • Locally Advanced or Metastatic Nonsquamous Non-Small Cell Lung Cancer: Pemetrexed 100 mg/500 mg injection, in combination with cisplatin, is used for the initial treatment of patients with locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC). It is also used as a maintenance therapy for patients whose disease has not progressed after four cycles of platinum-based first-line chemotherapy. Additionally, This medicine is used as a single-agent treatment for patients with locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC) who have previously undergone chemotherapy.  
  • Malignant Pleural Mesothelioma (Cancers of the Lungs and Chest): Pemetrexed 100 mg/500 mg injection, in combination with cisplatin is used for the treatment of patients with malignant pleural mesothelioma whose disease is unresectable or who are otherwise not candidates for curative surgery. 
 

Limitations of Use:

Pemetrexed 100 mg/500 mg injection is not approved for the treatment of patients with squamous cell non-small cell lung cancer. Pemetrexed 100 mg/500 mg injection is given alone or along with another anticancer medicine, such as cisplatin. Your healthcare provider (HCP) may also prescribe corticosteroids, folic acid, and vitamin B12. These help to reduce the side effects. Blood tests will be done before each infusion. These tests check if your kidney and liver functions are normal. They also check if you have enough blood cells to receive this medicine. Before starting treatment with 100 mg/500 mg injection, inform your doctor about any past or current medical conditions. This includes kidney problems, heart disorders, or fluid buildup in the lungs. Tell your healthcare provider (HCP) if you recently had radiotherapy. Also, report if you have taken or plan to take any vaccinations before this treatment.  

Dosage & Side Effects: 

Combination Use in Non-Small Cell Lung Cancer (NSCLC) and Mesothelioma:

The recommended dose of Pemetrexed injection is 500 mg/m2 administered as an intravenous (IV) infusion over 10 minutes on Day 1 of each 21-day cycle. The recommended dose of cisplatin is 75 mg/m2 infused over 2 hours beginning approximately 30 minutes after the end of Pemetrexed administration. Patients should receive appropriate hydration before and/or after receiving cisplatin.

Single-Agent Use in Non-Small Cell Lung Cancer:

The recommended dose of Pemetrexed is 500 mg/m2 administered as an intravenous (IV) infusion over 10 minutes on Day 1 of each 21-day cycle. Pemetrexed dose reductions or discontinuation may be required depending on toxicities from the preceding cycle of therapy. The most common side effects of Pemetrexed as a monotherapy are fatigue, nausea, and anorexia. Additional common side effects when used along with cisplatin include vomiting, anemia, neutropenia, stomatitis/pharyngitis, leukopenia, thrombocytopenia, and constipation.

Warning and Precautions

  • Before commencing Pemetrexed 100 mg/500 mg treatment, patients are prescribed folic acid and vitamin B12 as these have been shown to ease severe side effects. Moreover, physicians may also recommend corticosteroids to mitigate any potential skin reactions. While it is not obligatory to premedicate, doing so greatly improves the experience of the treatment.
  • Pemetrexed is capable of reducing blood cell production which can result in anemia, as well as increase the risk of infections and unexplained bruising. For this reason, patients are expected to have blood work done periodically. If they notice any unusual changes such as fever, extreme fatigue, or abnormal bleeding, they should consult with their doctors as they may be dealing with something far more serious.
  • Using Pemetrexed in patients with kidney problems should be approached with caution and close surveillance. The drug is excreted via the kidneys, so if their function is impaired, it may result in more harm than good. Staying hydrated and adhering to doctor’s orders will aid in minimizing health risks and complications, so it is something that should be done.
  • During Pemetrexed therapy, the physician will regularly monitor the patient’s blood cell counts, the state of their kidneys, and the condition of the liver, hence blood work will be necessary. These strategies assist the doctor in making modifications to avoid harmful consequences from the medications. Adhering to all necessary lab tests is paramount for treatment safety.
  • Undue pericardial effusion or ascitic fluid may lead to increased systemic toxicity of pemetrexed 100 mg/500 mg injection. Physicians may have to drain the fluid before initiation of therapy. Unusual swellings, breathing problems, or rapid weight changes should be attended to at once as they can be indicative of amiss health status.
  • Pregnant women must steer clear of this medication as it has proven harmful to the fetus. Pemetrexed is recommended not to be used by pregnant women using this medicine. Effective birth control has to be maintained throughout this procedure and for an indefinite period post-therapy. Seek medical consultation before tissue damage reconstruction after therapy.
  • There is potential that a nursing child might be affected by this medicine since pemetrexed can spread via breast milk. Therefore, breastfeeding should be discontinued throughout the duration and even for some time after the treatment is completed. All treatment options have to be discussed with physicians so that the mother remains safe and the child isn’t harmed. 

FAQ's

What is Pemetrexed?

Pemetrexed is a generic medicine. It is commonly available in 100 mg/500 mg injections and is primarily used for the treatment of non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma (cancers of the lungs and chest).

How is Pemetrexed injection supplied?

Pemetrexed is supplied in the form of Injection: 500 mg (5 mg/mL) or 100 mg (5 mg/mL) in a single-dose vial for intravenous (IV) use.

How much does Pemetrexed 100 mg/500 mg injection cost?

Please Call/WhatsApp: +91 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 to know the best Pemetrexed 100 mg/500 mg injection cost in India. If you want to buy Pemetrexed online, then THE INDIAN PHARMA (TIP) can help you access this medicinal product at the most competitive price through legal channels.

Is Pemetrexed 100 mg/500 mg injection available in India?

Pemetrexed is a pharmaceutical prescription medicinal product that can only be dispensed against a valid prescription from a treating physician. THE INDIAN PHARMA (TIP) can facilitate the supply of this drug to all locations after fulfilling the legal requirements (if applicable). Please contact us at +91 8130290915 | TOLL-FREE: 1800-889-1064 or at info@theindianpharma.com to buy generic Pemetrexed 100 mg/500 mg injections from India at the best price.

Can I get Pemetrexed 100 mg/500 mg injections even if I am not based in India?

THE INDIAN PHARMA (TIP) helps patients access Pemetrexed 100 mg/500 mg injections, which are not approved in their home country, against a valid prescription and in conformity with their respective country’s local laws and regulations.

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Where can I buy Pemetrexed 100 mg/500 mg injections from a Trusted Supplier?

  You can buy Pemetrexed 100 mg/500 mg injection online from India through a trusted generic medicine supplier, exporter, and contract manufacturer like THE INDIAN PHARMA (TIP). We are known for offering high-quality, affordable, and low-priced medicines. Contact us today for more information on availability and pricing.

Where can I get the best Pemetrexed 100 mg/500 mg injection Cost Price in India?

  The price of Pemetrexed 100 mg/500 mg injection is low and reasonable in India compared to other countries. If you wish to buy Pemetrexed online from India at an affordable price, contact us today. As trusted pharmaceutical wholesale distributors in India, we will help facilitate the legal supply of this therapeutic drug at the lowest possible prices.

Is it safe to buy Pemetrexed 100 mg/500 mg injections online from India?

Yes, one can buy Pemetrexed 100 mg/500 mg injections online at the best price from THE INDIAN PHARMA (TIP) if this drug is not registered or is unavailable in their country. TIP can help facilitate the supply of generic Pemetrexed injections through legal channels.

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