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Pazopanib Tablet

Pazopanib

 

  • API: Pazopanib
  • Packaging: 30 Tablets
  • Strength: 400 mg, 200 mg
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Description

Uses of Pazopanib :

Pazopanib is a kinase inhibitor primarily used for treating adults with advanced renal cell carcinoma (RCC) and advanced soft tissue sarcoma (STS), particularly in patients who have already undergone chemotherapy. This drug works by inhibiting specific proteins in cancer cells, which helps slow down or stop their growth.

However, the efficacy of Pazopanib for treating specific types of soft tissue sarcomas, like adipocytic soft tissue sarcoma and gastrointestinal stromal tumors (GIST), has not been established. This means it may not be as effective for those particular cancer types, and alternative treatments may be considered.

Dosage & Side Effects:

The recommended dosage of Pazopanib is 800 mg (four 200 mg tablets) orally once daily without food (at least 60 minutes before or 2 hours after a meal) until there is evidence of disease progression or unacceptable toxicity. The dosage should be modified for hepatic impairment and in patients taking certain concomitant medicines.

Swallow tablets whole. avoid crushing them due to the potential for an increased rate of absorption, which may affect systemic exposure. If a dose of Pazopanib is missed, it should not be taken if it is < 12 hours until the next scheduled dose.

The most common side effects of Pazopanib 400 mg/200 mg tablets in patients with renal cell carcinoma (RCC) (occurring in ≥ 20% of patients) are vomiting, diarrhea, hypertension, nausea, hair color changes, and anorexia. In patients with soft tissue sarcoma (STS) (occurring in ≥ 20% of patients), the side effects are diarrhea, fatigue, nausea, decreased weight, musculoskeletal pain, hypertension, hair color changes, decreased appetite, tumor pain, vomiting, dyspnea, headache, dysgeusia, and skin hypopigmentation.

Warnings and Precautions

  • Treatment with this medicine may cause severe or fatal liver damage. Monitor liver function before starting treatment and regularly during therapy. Discontinue therapy if elevated liver enzymes or signs of liver failure appear. Patients with pre-existing liver conditions require extra caution.
  • Pazopanib may lead to cardiac dysfunction, including heart failure or decreased ejection fraction. Regularly monitor heart function in patients with cardiac risk factors. Discontinue treatment if serious heart issues develop during therapy. Consult your doctor before use with existing heart conditions.
  • Severe bleeding (hemorrhagic) events have been reported with Pazopanib 400 mg or 200 mg tablets, including fatal cases. Avoid use in patients with a history of significant bleeding or those undergoing surgery. Monitor closely for signs of internal bleeding and immediately report any unusual symptoms to your healthcare provider.
  • This medicine can increase the risk of arterial thromboembolic events, such as strokes and heart attacks. Patients with a history of cardiovascular disease should be closely monitored. Stop this treatment if severe arterial clotting events are detected during treatment.
  • The use of this therapeutic drug may increase the risk of venous thromboembolic events, such as deep vein thrombosis or pulmonary embolism. Patients at high risk of clotting should be monitored closely, and treatment may need to be discontinued if such events occur.
  • Rare cases of thrombotic microangiopathy (TMA), a condition that damages small blood vessels, have been reported with Pazopanib tablets. Monitor patients for symptoms such as high blood pressure or decreased kidney function. Discontinue therapy if TMA is diagnosed during therapy.
  • Pazopanib 200 mg/400 mg can cause hypothyroidism in some patients. Monitor thyroid function before and during treatment. Patients may require thyroid hormone replacement therapy if levels drop significantly. Regular checkups are essential to prevent long-term complications related to thyroid dysfunction.
  • Pazopanib may trigger tumor lysis syndrome (TLS), a potentially life-threatening condition that results from rapid tumor breakdown. Patients with large tumor burdens should be monitored closely. Preventive measures, such as hydration and medications, may be necessary to reduce TLS risk.
  • This medicine can cause embryo-fetal toxicity, leading to potential harm to a developing fetus. Pregnant women should avoid using Pazopanib, and effective contraception must be used during treatment and for at least two weeks after the final dose to prevent pregnancy.

FAQ

How is Pazopanib supplied?

Pazopanib is supplied in Tablets of 400 mg and 200 mg dosage strength for oral administration.

How much does Pazopanib 400 mg/200 mg Tablet cost?

Please Call/WhatsApp: +91 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 to know the exact Pazopanib 400 mg/200 mg cost in India. If you want to buy Pazopanib online, then THE INDIAN PHARMA (TIP) can help you access this medicinal product at the most competitive price through legal channels.

Is Pazopanib 400 mg/200 mg Tablet available in India?

Pazopanib is a pharmaceutical prescription medicinal product that can only be dispensed against a valid prescription from a treating physician. THE INDIAN PHARMA (TIP) can facilitate the supply of this drug to all locations after fulfilling the legal requirements (if applicable). Please contact us at +91 8130290915 | TOLL-FREE: 1800-889-1064 or at info@theindianpharma.com to buy Pazopanib online from India at the best price.

Can I get Pazopanib 400 mg/200 mg Tablets even if I am not based in India?

THE INDIAN PHARMA (TIP) helps patients access Pazopanib 400 mg/200 mg Tablets, which are not approved in their home country, against a valid prescription and in conformity with their respective country’s local laws and regulations.

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Where can I buy Pazopanib 400 mg/200 mg Tablets from a Trusted Supplier?

You can buy Pazopanib 400 mg/200 mg Tablets from The Indian Pharma (TIP), a reliable generic medicine supplier from India. We are known for offering high-quality, affordable, and low-priced medicines. Kindly contact us for more information on availability and pricing.

Where can I get the best Pazopanib Cost Price in India?

The price of Pazopanib 400 mg/200 mg Tablet is low and reasonable in India compared to other countries. If you wish to buy Pazopanib online from India at an affordable price, contact us today. As trusted pharmaceutical wholesale distributors in India, we will help facilitate the supply of this therapeutic drug at the lowest possible prices.

Is it safe to buy Pazopanib 400 mg/200 mg Tablets online from India?

Yes, one can buy Pazopanib 200 mg/400 mg online at the best price from THE INDIAN PHARMA (TIP) if this therapeutic drug is not registered or is unavailable in their country. TIP can help facilitate the supply of Pazopanib 400 mg/200 mg tablets through legal channels.

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