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Lapatinib Tablet

Lapatinib 250 MG Tablets

Brand Name: Hertab
API: Lapatinib
Packaging: Tablets
Strength: 250 mg
Manufacturer: Hetero Healthcare

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Description

Uses of Lapatinib Tablets:

Lapatinib Tablets, supplied generically under the brand Hertab is a type of medication called a kinase inhibitor. It is used alongside:

  • Capecitabine to treat patients with advanced or metastatic breast cancer whose tumors have too much of the HER2 protein and who have already been treated with other therapies, including anthracyclines, taxanes, and trastuzumab.
  • Letrozole for postmenopausal women with hormone receptor-positive metastatic breast cancer that also overexpresses the HER2 protein, and who are suitable for hormonal therapy.

Dosage & Side Effects:

For advanced or metastatic breast cancer, the recommended dosage of Lapatinib is 1,250 mg (5 tablets) once daily for 21 days, combined with capecitabine 2,000 mg/m²/day (split into 2 doses about 12 hours apart) for 14 days in a 21-day cycle. For hormone receptor-positive, HER2-positive metastatic breast cancer, Lapatinib should be taken at 1,500 mg (6 tablets) once daily with letrozole 2.5 mg once daily. Take Lapatinib at least 1 hour before or after a meal, and take capecitabine with food or within 30 minutes after eating. Do not split the daily dose of Lapatinib.

When taking Lapatinib with capecitabine, the most frequently occurring side effects (affecting more than 20% of patients) include diarrhea, palmar-plantar erythrodysesthesia (a skin condition affecting the hands and feet), nausea, rash, vomiting, and fatigue. On the other hand, when Lapatinib is used with letrozole, the most common side effects (affecting 20% or more of patients) are diarrhea, rash, nausea, and fatigue.

Warning and Precautions:

  • Lapatinib may cause decreased left ventricular ejection fraction (LVEF), which can lead to heart failure. Monitor cardiac function regularly, especially in patients with pre-existing heart conditions. Discontinue if significant LVEF reduction is observed.
  • Hepatic toxicity, including severe liver damage, can occur. Monitor liver enzymes regularly. Discontinue lapatinib if elevated liver enzymes persist or if jaundice, hepatic dysfunction, or severe liver injury is observed.
  • Treatment with generic Lapatinib (Hertab 250 mg tablets) should be used with caution in patients with severe hepatic impairment. Dose adjustments may be necessary, and close monitoring is essential.
  • Diarrhea is a common side effect. Manage with antidiarrheal medications and ensure adequate hydration. Persistent or severe diarrhea can lead to dehydration and electrolyte imbalances.
  • Interstitial lung disease (ILD) and pneumonitis can occur, presenting as cough, dyspnea, or fever. Discontinue Hertab 250 mg tablets if ILD or pneumonitis is suspected and initiate appropriate treatment.
  • This therapeutic drug can prolong the QT interval, increasing the risk of life-threatening arrhythmias. Monitor electrocardiograms (ECGs) regularly, especially in patients with pre-existing heart conditions or those taking other QT-prolonging drugs.
  • Severe skin reactions, including Stevens-Johnson syndrome, can occur. Monitor for signs of rash or severe skin reactions and discontinue treatment if such reactions develop.
  • Treatment with Lapatinib 250 mg tablets can cause harm to a developing fetus. Women of childbearing potential should use effective contraception during treatment and avoid pregnancy.

FAQ's

What is the active substance in HERTAB 250 mg?

Lapatinib is the active substance in HERTAB 250 mg.

How is HERTAB (Lapatinib) supplied?

Generic Lapatinib is supplied in a dosage strength of 250 mg, consisting of 30 tablets and 150 tablets respectively for oral use.

Who has introduced the generic version of Lapatinib in India?

Hetero Pharmaceuticals has introduced a generic version of Lapatinib in India under the brand name Hertab 250 mg. This new formulation of Lapatinib 250 mg tablets represents a significant advancement in the treatment options for metastatic breast cancer in the country.

How much does Lapatinib (HERTAB 250 mg) cost?

Please Call/WhatsApp: +91 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 to know the exact Lapatinib cost in India. If you want to buy Lapatinib online, then THE INDIAN PHARMA (TIP) can help you access this medicinal product at the most competitive price through legal channels.

Is Lapatinib (HERTAB) available in India?

Lapatinib is a pharmaceutical prescription medicinal product that can only be dispensed against a valid prescription from a treating physician. THE INDIAN PHARMA (TIP) can facilitate the supply of this drug to all locations after fulfilling the legal requirements (if applicable). Please contact us at +91 8130290915 | TOLL-FREE: 1800-889-1064 or at info@theindianpharma.com to buy Lapatinib from India at the best price.

Can I get Lapatinib tablets even if I am not based in India?

THE INDIAN PHARMA (TIP) helps patients access Lapatinib, which is not approved in their home country, against a valid prescription and in conformity with their respective country’s local laws and regulations.

Send your inquiry to find generic Lapatinib in Ukraine, Saudi Arabia, Jordan, Mexico, Uzbekistan, Brazil, Chile, Colombia, Peru, Venezuela, Romania, Switzerland, Georgia, Turkey, Italy, Sri Lanka, Afghanistan, Germany, Azerbaijan, Latvia, Poland, Armenia, Kazakhstan, Moldova, Tajikistan, Mongolia, Algeria, Mauritius, Uganda, Zimbabwe, Australia, New Zealand, China, Cambodia, Indonesia, Malaysia, Philippines, Singapore, Thailand, Vietnam, Hong Kong, UAE, Iran, Argentina, UK, Slovakia, Turkmenistan, Trinidad & Tobago, Liberia, France, Slovak Republic, Egypt, Guinea, Kenya, Benin, Dominican Republic, Nepal, Ethiopia, Somalia, United Arab Emirates, Cameroon, St. Lucia, Mali, Tanzania, Congo (The Democratic Republic Of The Congo), Côte d’Ivoire, Cayman Islands, Nigeria, Zambia, Qatar, Madagascar, Guatemala, Oman, Morocco, Hungary, Macedonia (The Former Yugoslav Republic Of), Namibia, United States, Jamaica, Congo, Serbia, Myanmar, South Africa, Sudan, Ecuador, Fiji, Malawi, Panama, Nicaragua, Belize, Greece, Bosnia & Herzegovina, Taiwan, Senegal, Burkina Faso, Papua New Guinea, Ghana, Paraguay, Bangladesh, Malta, Maldives, Niger, Sierra Leone, Lebanon, Barbados, Togo, Pakistan, St. Kitts-Nevis-Anguilla, Eritrea, Gabon, Mozambique, Grenada, El Salvador, Russia, Guyana, British Virgin Islands, Lithuania, Botswana, Haiti, Saint Vincent And The Grenadines, Netherlands, Guatemala, Angola, Laos, Kyrgyzstan, Yemen, Dominica, Canada, Burundi, Kazakhstan, Belgium, Moldova (Republic Of), Laos (People’s Democratic Republic), Saint Kitts And Nevis, Saint Lucia, Seychelles, Rwanda, Libya, Ireland, St. Vincent, Spain, Bolivia, Netherlands Antilles, Suriname, Japan, Namibia, Albania, Mauritania, Bahamas, Dominican Republic, Bulgaria, Portugal, Yemen, Korea, Costa Rica, Tunisia, and Gambia.

Where can I get the best Lapatinib HERTAB 250 mg Cost Price in India?

Lapatinib HERTAB 250 mg price is low and reasonable in India in comparison to other countries. If you wish to buy HERTAB Lapatinib 250 mg tablets online from India at an affordable price, contact us today. We will help facilitate the supply of HERTAB 250 mg tablets at the lowest possible prices.

Is it safe to buy HERTAB 250 mg (Generic Lapatinib) online from India?

Yes, one can buy generic Lapatinib online (HERTAB) at the best price from THE INDIAN PHARMA (TIP) if this medicine is not registered or is unavailable in their country. TIP can help facilitate the supply/export of Lapatinib tablets through legal channels.

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