Description
Uses of Medicine:
Nitisinone 2 mg/5 mg/10 mg is a hydroxy-phenylpyruvate dioxygenase inhibitor. Patients, Healthcare Professionals (HCP), or Hospitals can buy Nitisinone 2 mg/5 mg/10 mg Capsules online from India through THE INDIAN PHARMA (a trusted Nitisinone Supplier, Exporter, and Contract Manufacturer in India) for the management and treatment of:- Hereditary tyrosinemia type 1 (adults, adolescents, and children)
- Alkaptonuria (adults)
Nitisinone 2 mg/5 mg/10 mg is a medicine that falls under the group of medicines called enzyme inhibitors. The drug is widely used for the treatment of two rare conditions—hereditary tyrosinemia type 1 (HT-1) and alkaptonuria (AKU). HT-1 can affect infants, children, and adults, whereas AKU is only seen in adult patients. Nitisinone works by blocking the breakdown of an amino acid known as tyrosine in the body. When tyrosine is not broken down appropriately, hazardous substances can accumulate and cause life-threatening health complications. This medicinal product helps reduce the accumulation of those hazardous substances. If you are on Nitisinone for HT-1 or AKU, your doctor will most likely recommend a special diet as well to make managing the condition with the medicine much easier.
Do not take Nitisinone 2 mg/5 mg/10 mg capsules if you are allergic to this medicine or any of its ingredients. Before initiating treatment with this medicine, it is very necessary to consult your healthcare provider (HCP). Let your doctor know in case you have any ongoing or known liver or kidney complications, as these may affect your treatment strategy. If you have a known history of low white blood cell count (leukopenia) or low platelet count (thrombocytopenia), let your doctor know. These conditions may be responsible for increasing the risk of side effects or complications during treatment. Before starting this treatment, your doctor will check your blood to make sure your white blood cells (WBCs) and platelets are at safe levels.
While on treatment with Nitisinone 2 mg/5 mg/10 mg Capsule, your doctor will monitor your health closely. Regular eye exams will be done to check for any changes in vision or other eye-related side effects. At intervals, your physician will also take blood samples to assess treatment efficacy and any potential hematologic adverse effects. If you are treated for HT-1, regular liver function tests would be done to see if the liver is healthy and the medication is working as intended.
Promptly respond to any scheduled check-ups with your provider after initiating treatment; these are generally every six months, but can be more frequent depending on what your provider deems necessary. These visits are vital for managing any possible side effects of the treatment. If you experience anything out of the ordinary while you are on Nitisinone 2 mg/5 mg/10 mg Capsule, get in touch with your physician without delay. Abide by the instructions provided concerning treatment measures to protect your health, including those related to prescribing, diet, and monitoring.
Dosage & Side Effects:
The recommended starting dosage of Nitisinone is 0.5 mg/kg orally twice daily. In patients aged 5 years and older who have undetectable serum and urine succinylacetone concentrations after a minimum of 4 weeks on a stable dosage of nitisinone, the total daily dose may be given once daily. Titrate the dosage depending on biochemical and/or clinical response. The maximum total daily dosage of Nitisinone is 2 mg/kg orally.The most common side effects of Nitisinone 2 mg/5 mg/10 mg oral capsules are elevated tyrosine levels, eye pain, thrombocytopenia, corneal opacity, leukopenia, conjunctivitis, keratitis, photophobia, blepharitis, cataracts, dry skin, granulocytopenia, epistaxis, pruritus, exfoliative dermatitis, maculopapular rash, and alopecia.
