Fact of Medicine

  • Medicine Name: Abacavir-Lamivudine
  • API: Abacavir/Lamivudine
  • Packaging: Tablets
  • Strength: 600mg/300mg
Get Price


Uses of medication: Abacavir and lamivudine is a fixed-dose tablet, in combination with other antiretroviral agents, are used for the treatment of human immunodeficiency virus type 1 (HIV-1) infection. Dosage: The recommended dosage of abacavir lamivudine combination medicine for adults and pediatric patients weighing at least 25 kg is 1-Tablet (600mg/300mg) taken orally once daily, in combination with certain other antiretroviral agents, with or without food. Because abacavir/lamivudine tablet is a fixed-dose tablet and cannot be dose adjusted, it is not recommended for:
  • patients with creatinine clearance not beyond 50mL per minute.
  • patients with mild hepatic impairment. This FDC medicine is contraindicated in patients with moderate/severe hepatic impairment.
Treatment Reactions: The most commonly reported side effects due to Abacavir/Lamivudine include:
  • drug hypersensitivity
  • insomnia
  • nausea
  • diarrhea
  • fatigue/malaise
  • dizziness/vertigo
  • headache/migraine
  • depression/depressed mood
Warnings and Precautions:
  • Abacavir/lamivudine tablets are contraindicated in patients who have the HLA-B*5701 allele, in patients with known hypersensitivity reaction to abacavir or lamivudine, and in patients with moderate/severe hepatic impairment.
  • Clinical and laboratory evidence of exacerbations of hepatitis has appeared after the interruption of lamivudine. Closely monitor patients for both clinical and laboratory follow-up for at least some months after stopping abacavir lamivudine 600 mg treatment.
  • Safety and efficacy of medicine lamivudine have not been assessed for treatment of chronic hepatitis B in subjects dually infected with HIV-1 & HBV. Emergence of hepatitis B virus variants associated with resistance to lamivudine have been observed in HIV-1-infected subjects who have been treated with lamivudine-containing antiretroviral regimens in the presence of concurrent infection with hepatitis B virus.
  • Lactic acid build up in the bloodstream and severely enlarged liver with steatosis, including fatal cases, have been seen with nucleoside analogues, including abacavir 600 mg & lamivudine 300 mg (components of abacavir and lamivudine tablets). A maximum of these cases have been seen in women. Female sex and obesity are the risk factors for this development in patients treated with antiretroviral nucleoside analogues.
  • Immune reconstitution inflammatory syndrome may occur in patients taking treatment with cART, including abacavir and lamivudine. During the initial phase of cART, patients whose immune systems respond may develop an inflammatory response to indolent or residual opportunistic infections (such as cytomegalovirus, Mycobacterium avium infection, Pneumocystis jirovecii pneumonia, or tuberculosis), which may necessitate further assessment and treatment.
  • Autoimmune disorders (Graves’ disease, polymyositis, and Guillain-Barr¡SR syndrome) may also occur in the setting of immune reconstitution, however, the time to onset is more variable, and can occur several months after initiation of Abacavir 600 mg/ Lamivudine 300 mg treatment.
  • As a precaution, the underlying risk of coronary heart disease needs to be considered when using antiretroviral therapies (ARTs), including abacavir, and action considered to minimize all modifiable risk factors (hypertension, diabetes mellitus, hyperlipidemia, smoking).
  • Patients are advised that there is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to abacavir and lamivudine during pregnancy. Women with HIV-1 positive should avoid breastfeeding because the infection can be passed to the baby in breast milk.

More information

Storage: Abacavir/lamivudine is available as tablets. Each tablet contains abacavir 600 mg as abacavir sulfate and lamivudine 300 mg. These are orange coloured, capsule shaped, biconvex, film coated tablets. Store the Tablets of Abacavir/Lamivudine at 25°C (77°F); excursions permitted to 15-30°C (59-86°F). Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship ABACAVIR AND LAMIVUDINE at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality and delivery for the ABACAVIR AND LAMIVUDINE Tablets. Buying Procedure: In order to buy ABACAVIR AND LAMIVUDINE, you can contact us at our Toll-free Number 1800 889 1064 or on WhatsApp Number +91 8130290915 or an Email to us at: info@theindianpharma.com along with your Identity Proof, Valid Prescription Letter and Medical Reports. Conclusion: For several years, abacavir/lamivudine-FDC has been successfully used in zillions of HIV-infected patients as the NRTI backbone of cART with minimal side effects and excellent virologic suppression. Despite some limitations, abacavir/lamivudine-FDC has a smaller, but vital role in the management of HIV infection.

Commonly asked questions

What is the brand name for Abacavir/Lamivudine? Abacavir/Lamivudine, sold under the brand name Kivexa. It is a fixed-dose combination (FDC) antiretroviral medicinal product authorized to treat HIV/AIDS. What class of drug is Abacavir-Lamivudine? Abacavir-Lamivudine both belong to a class of drugs called nucleoside reverse transcriptase inhibitors (NRTIs). It is not a cure for HIV/AIDS infection. How Abacavir-Lamivudine is taken?  Abacavir-Lamivudine is taken orally (by mouth) in tablet form. How much does Abacavir-Lamivudine cost? The abacavir-lamivudine cost in India typically depends on a wide range of available generic brands. In order to procure it authentically, kindly reach out to us either via TOLL-FREE Number: 1800 889 1064 or Call/Whatsapp: +91 8130290915, or Email: info@theindianpharma.com. Where can I get Abacavir Lamivudine at the best price? To get the best abacavir lamivudine price in India, you can get in touch with The Indian Pharma (TIP), or any other Pharmaceutical Wholesaler Company which is certified by the higher authorities like WHO-GDP & ISO 9001:2008. A valid prescription is required while buying Abacavir Lamivudine. Can I get Abacavir-Lamivudine even if I am not based in India? The Indian Pharma helps patients in accessing or importing Abacavir-Lamivudine, not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country. Is it safe to buy Abacavir-Lamivudine online from India?  Yes, You can buy abacavir lamivudine from India legitimately from https://theindianpharma.com/ if the product has not been approved or is not available in your home country.