Ayvakit (Avapritinib)

  • Brand Name: Ayvakit
  • Innovator Brand Name: Ayvakit
  • API: Avapritinib
  • Dosage Form: 30 Tablets
  • Strength: 100/200/300mg
  • Manufacturer Name: Blueprint Medicines Corporation
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Ayvakit Uses:

Ayvakit (Avapritinib) is a kinase inhibitor used for the treatment of adult patients with unresectable or metastatic gastrointestinal stromal tumor (GIST) harboring a platelet-derived growth factor receptor alpha (PDGFRA) exon-18 mutation, including PDGFRA D842V mutations.

Dosage: The recommended dosage of Avapritinib is 300 mg orally once daily on an empty stomach, at least 1 hour before and 2 hours after a meal. Continue treatment until the disease is progressive or unacceptable toxicity occurs. Do not make up for a forgotten or missed dose within 8 hours of the next scheduled Avapritinib dose. Do not take an additional dose if vomiting occurs after Avapritinib, but continue with the next scheduled dose.

Side Effects: The most commonly reported avapritinib side effects (incidence ≥ 20%) include:

  • edema
  • nausea
  • vomiting
  • decreased appetite
  • diarrhea
  • hair color changes
  • increased lacrimation
  • abdominal pain
  • constipation
  • rash
  • dizziness
  • fatigue/asthenia
  • cognitive impairment

Warnings and Precautions:

  • Patients with avapritinib drug should contact their health specialist immediately if experiencing neurological signs and symptoms that may be associated with intracranial hemorrhage.
  • Pregnancy status should be verified of females of reproductive potential prior to initiating therapy with avapritinib 300 mg. It can cause fetal harm when administered to pregnant women.
  • Women should not breastfeed during treatment with avapritinib and for 2 weeks following the final dose.
  • Patients and caretakers should notify their health specialist if they experience new or worsening CNS symptoms during therapy with avapritinib tablets. Patients should not drive/operate hazardous machinery if they are experiencing CNS adverse reactions.

More Info

Storage: Store Ayvakit Tablets at room temperature between 20°C to 25°C (68°F to 77°F); excursions are permitted from 15°C to 30°C (59°F to 86°F). Store it in the original, labeled container and in a dry location. Availability in India: The Indian Pharma helps connect buyers with suppliers who can ship the AYVAKIT at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality as well as delivery for the AYVAKIT Tablets. Buying Procedure: In order to buy AYVAKIT, you can contact us at our TOLL-FREE Number: 1800 889 1064 or on WhatsApp number +919310090915 or an Email to us at: info@theindianpharma.com along with the legitimate ID Proof, Standard Prescription and Medical Reports. Conclusions: Avapritinib therapy has manageable toxicity with meaningful clinical activity as 4’th-line or later treatment in some patients with gastrointestinal stromal tumor with KIT or PDGFRA mutations.


What is Ayvakit? Ayvakit is a prescription medication approved to treat adults with: gastrointestinal stromal tumor that cannot be treated with surgery or that is metastatic, and that is caused by certain abnormal PDGFRA genes. advanced systemic mastocytosis (AdvSM), including aggressive systemic mastocytosis (ASM), systemic mastocytosis with an associated hematological neoplasm (SM-AHN), and mast cell leukemia (MCL). Is Ayvakit Approved by the FDA? Yes. What dosage strengths Ayvakit Tablets are available? Tablets are available in three dosage strengths, which are as follows:
  • ayvakit 100 mg
  • ayvakit 200 mg
  • ayvakit 300 mg
What does Ayvakit contain as an active substance? The medication Ayvakit specifically contains the active substance Avapritinib. How much does ayvakit cost? The ayvakit price in India usually can vary depending on the wholesaler/pharmacy you visit. Ayvakit is available as a brand name drug only, a generic version is not yet available. What is the best price for Avapritinib? Please contact Toll-free: +91 1800 889 1064 |+919310090915 for avapritinib price in India. We take the guarantee of quality and delivery anywhere in the world as per the buyer’s requirements. Can I get Ayvakit (Avapritinib) even if I am not based in India? The Indian Pharma helps patients in accessing or importing Ayvakit (Avapritinib), not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country.