Rucaparib

  • Brand Name: Nuparp
  • API: Rucaparib
  • Packaging: 60 Tablets
  • Strength: 300 mg, 250 mg, 200 mg
  • Manufacturer: Zydus Cadila
Get Price

Description

Uses of Rucaparib Medicine:

Rucaparib 300 mg/250 mg/200 mg tablets, supplied under the generic brand Nuparp is an anti-cancer drug classified as a PARP (poly ADP-ribose polymerase) inhibitor. It is prescribed to help sustain the effects of prior treatments for certain cancers, including ovarian cancer, fallopian tube cancer (cancer affecting the tubes that carry eggs from the ovaries to the uterus), and primary peritoneal cancer (cancer in the tissue lining the abdomen). Rucaparib 300 mg/250 mg/200 mg is specifically used in adults whose cancer has returned and who have fully or partially responded to earlier chemotherapy.

Additionally, Rucaparib is indicated for patients with specific BRCA gene mutations who have already undergone at least two previous chemotherapy regimens. It is also used as maintenance therapy after chemotherapy when the tumor has shrunk, helping to extend the benefits of the treatment.

Dosage & Side Effects of Rucaparib tablets:

The standard dosage of Rucaparib tablets is 600 mg, taken as two 300 mg tablets by mouth twice a day, totaling a daily dose of 1,200 mg. Treatment should be continued until there are signs of disease progression or side effects that cannot be tolerated.

If a dose is missed, patients should take their next scheduled dose as usual without doubling up. If a dose is vomited, it should not be replaced. For patients using Rucaparib to treat metastatic castration-resistant prostate cancer (mCRPC), a concurrent gonadotropin-releasing hormone (GnRH) analog is recommended, or they should have previously undergone a bilateral orchiectomy.

The most commonly reported side effects of Rucaparib 300 mg, 250 mg, and 200 mg tablets among patients with ovarian cancer are nausea, fatigue (including asthenia), anemia, vomiting, diarrhea, decreased appetite, thrombocytopenia, dysgeusia, neutropenia, blood creatinine increased, dyspnea, dyspepsia, dizziness, photosensitivity reaction, and leukopenia.

The most commonly reported side effects among patients with BRCAmutated mCRPC are rash, ALT/AST increased, decreased appetite, fatigue (including asthenia), nausea, anemia, constipation, vomiting, thrombocytopenia, and diarrhea.

Warnings and Precautions

  • Treatment with Rucaparib can lead to the development of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), both of which are rare but serious conditions. Patients who experience symptoms such as unexplained fatigue, easy bruising, frequent infections, or abnormal blood counts should inform their healthcare provider immediately. Blood monitoring is recommended throughout treatment to detect early signs of these conditions.
  • Treatment with this therapeutic drug may cause harm to a developing fetus when administered to pregnant women. Women of childbearing potential should use effective contraception during treatment and for at least 6 months after the last dose. If a patient becomes pregnant during treatment, they should inform their healthcare provider right away to discuss potential risks to the fetus.
  • Rucaparib 300 mg/250 mg/200 mg may cause bone marrow suppression, leading to conditions such as anemia, neutropenia (low white blood cell count), and thrombocytopenia (low platelet count). Regular blood tests are required to monitor for these potential side effects. Patients should notify their doctor if they experience symptoms such as persistent tiredness, unusual bleeding, or increased susceptibility to infections.
  • Rucaparib can cause liver enzyme elevations, indicating potential liver damage. Routine liver function tests are recommended before starting treatment and periodically during treatment to detect any hepatic issues. If patients experience symptoms such as jaundice (yellowing of the skin or eyes), dark urine, or upper abdominal pain, they should inform their healthcare provider.
  • Treatment with Rucaparib has been associated with increased sensitivity to sunlight, potentially leading to severe sunburn. Patients should be advised to use sunscreen, wear protective clothing, and avoid prolonged sun exposure while taking the medication.
  • Although rare, Rucaparib may affect heart function, leading to changes in heart rhythm. Patients with a history of cardiovascular disease should be closely monitored during treatment. Symptoms such as shortness of breath, chest pain, or palpitations should be reported to a healthcare provider immediately.

FAQ

What is Nuparp?

Nuparp is an Indian generic brand that contains Rucaparib as its active ingredient. This therapeutic drug is commonly available in 300 mg/250 mg/200 mg tablets and is primarily used in the treatment of Ovarian Cancer and Prostate Cancer.

How are Rucaparib 300 mg/250 mg/200 mg tablets administered?

Rucaparib tablets (300 mg/250 mg/200 mg) are administered orally, typically twice daily, with or without food. The exact dosage is prescribed by a healthcare provider based on individual patient needs.

How should I store Rucaparib 300 mg/250 mg/200 mg Tablets?

Store Rucaparib tablets at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).

How much does Rucaparib 300 mg/250 mg/200 mg cost in India?

Rucaparib 300 mg/250 mg/200 mg tablets are available in India at competitive and reasonable prices, though the cost may vary depending on the supplier and location. For those looking to buy Rucaparib online legally and without hassle, Indian Generic Medicines (IGM) offers an easy and reliable solution. To inquire about the current Rucaparib 300 mg/250 mg/200 mg price in India, simply call us at +91 8130290915 or dial our TOLL-FREE Number 1800-889-1064. You can also email us at info@indiangenericmedicines.com for detailed pricing information and assistance.

Where can I get Rucaparib 300 mg/250 mg/200 mg tablets at the best price?

To ensure you receive Rucaparib at the most competitive price, reach out to Indian Generic Medicines (IGM) today. We are committed to offering the best prices for Rucaparib from India, and we can match or beat the cost offered by other suppliers or distributors in the market. Contact us via Call/WhatsApp at +91 8130290915, or use our TOLL-FREE Number 1800-889-1064. Alternatively, you can email us at info@indiangenericmedicines.com. Please note that a valid medical prescription is required to purchase Rucaparib.

Are Rucaparib 300 mg/250 mg/200 mg tablets available in India?

Yes, Rucaparib 300 mg/250 mg/200 mg tablets are available in India as a prescription medicine. This pharmaceutical drug can be legally obtained through India’s authorized distributor network, which spans major cities such as Hyderabad, Mumbai, Bangalore, Ahmedabad, Delhi, Kolkata, Chennai, and Pune. To buy Rucaparib tablets online from India, a valid prescription from a healthcare professional is required. Indian Generic Medicines (IGM) can assist you in sourcing generic Rucaparib from India’s top suppliers.

Can you send Generic Rucaparib 300 mg/250 mg/200 mg tablets to foreign destinations?

Indian Generic Medicines (IGM) specializes in the export and delivery of generic Rucaparib 300 mg/250 mg/200 mg tablets at the lowest prices. We facilitate the shipment of Rucaparib tablets to various countries, including but not limited to UAE, Australia, the USA, Saudi Arabia, Canada, the UK, Germany, France, Belgium, Bulgaria, Brazil, Kenya, Japan, and South Africa. Whether you are located in Australia, North America, South America, Eastern Europe, Western Europe, the Middle East, Africa, Central America, or Asia, IGM can assist in delivering generic Rucaparib as per your requirements. For more information on international shipping options, contact us today.

What Is the procedure for buying Rucaparib from Indian Generic Medicines?

To buy Rucaparib from Indian Generic Medicines (IGM), patients need to fill out the order form or send an email to info@indiangenericmedicines.com. Alternatively, you can send a WhatsApp message to +91 8130290915 or call our TOLL-FREE Number 1800-889-1064. After receiving your inquiry, we will provide you with details regarding Rucaparib’s price in India and the procurement process. Please note that your order will only be confirmed once we receive a valid prescription from your physician.

Is it safe to buy Rucaparib 300 mg/250 mg/200 mg tablets online from India?

Yes, buying Rucaparib online from India through Indian Generic Medicines (IGM) is safe, especially if the drug is not registered or unavailable in your country. IGM facilitates the legal export of Rucaparib 300 mg/250 mg/200 mg tablets to various countries, ensuring that you receive genuine medicine. Our service ensures compliance with all necessary regulations, providing a secure and reliable way to access Rucaparib from India.

× How can I Help you?