Dobutamine

  • Brand Name: Dobustat
  • API: Dobutamine
  • Packaging: 5mL Vial
  • Strength: 250 mg
  • Manufacturer: Samarth Life Sciences Pvt Ltd
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Description

Dobustat (Dobutamine Injection 250 MG/5mL )

Uses of Medicine: Dobutamine injection, available generically under the brand Dobustat, is a crucial therapeutic drug used for the treatment of heart failure and cardiogenic shock by enhancing the heart’s pumping ability. It stimulates beta-1 adrenergic receptors, leading to increased cardiac output without significantly affecting heart rate. This medicinal product is commonly administered in intensive care units, providing critical support for patients with acute cardiac conditions.

Dosage and Side Effects

The recommended dosage of Dobutamine typically begins with a low dose of 0.5 to 1.0 mcg/kg/min and can increase up to a maximum of 40 mcg/kg/min. Initial doses often range from 2.5 to 5.0 mcg/kg/min, while higher doses can reach 20 mcg/kg/min. Before administration, it is crucial to inspect parenteral drug products for particulate matter and discoloration. The infusion rate should be adjusted based on the patient’s response, considering factors like systemic blood pressure, heart rate, and urine flow. Optimal rates generally fall between 2 to 20 mcg/kg/min, with rare instances requiring up to 40 mcg/kg/min. For stress echocardiogram and stress nuclear tests, dosing starts at 5 mcg/kg/min, increasing every 3 to 5 minutes until the target heart rate is reached.

The most common side effects of Dobutamine 250 mg/5mL injection are increased heart rate, blood pressure changes, nausea, headaches, palpitations, and shortness of breath.

Warning and Precautions

  • Patients with a known allergy to Dobutamine injection should strictly avoid its use due to the risk of severe hypersensitivity reactions, including life-threatening anaphylaxis. If symptoms of an allergic reaction occur, immediate medical attention is crucial.
  • Treatment with this therapeutic drug can induce arrhythmias, especially in patients with a history of heart rhythm disorders. Continuous ECG monitoring during administration is essential to detect and address any irregularities promptly.
  • Moreover, Dobutamine 250 mg/5mL may cause a significant rise in blood pressure, particularly in patients with pre-existing hypertension. Close monitoring of blood pressure levels is necessary, with appropriate adjustments made as required. Conversely, in some cases, this drug may paradoxically lead to hypotension. Therefore, careful titration and monitoring are vital to maintaining optimal blood pressure levels.
  • Another important consideration is the potential for tachyphylaxis with prolonged use of Dobustat injection. This phenomenon, where the effectiveness of the drug diminishes over time, underscores the need for regular assessment of the patient’s response to the medication.
  • Finally, the safety profile of this medicinal product in pregnant or nursing women has not been conclusively established. The drug should only be used in these populations if the potential benefits outweigh the risks to the fetus or infant.
  • When managing patients on Dobutamine, it is critical to be aware of these risks and to monitor the patient closely throughout treatment. Careful consideration of the patient’s medical history and continuous monitoring are essential to optimizing outcomes and minimizing potential adverse effects.

FAQ's

What is the active substance in Dobustat?

Dobutamine is the active substance in Dobustat.

How is Dobutamine supplied?

This therapeutic drug is supplied in injection: 250 mg/5mL for intravenous (IV) administration.

Who has introduced the generic version of Dobutamine in India?

Samarth Life Sciences Pvt Ltd has introduced a generic version of Dobutamine in India under the brand Dobustat.

How much does Dobutamine 250 mg/5mL cost?

Please Call/WhatsApp: +91 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 to know the exact Dobutamine 250 mg/5mL cost in India. If you want to buy Dobutamine online, then THE INDIAN PHARMA (TIP) can help you access this medicinal product at the most competitive price through legal channels.

Is Dobutamine 250 mg/5mL available in India?

Dobutamine is a pharmaceutical prescription medicinal product that can only be dispensed against a valid prescription from a treating physician. THE INDIAN PHARMA (TIP) can facilitate the supply of this drug to all locations after fulfilling the legal requirements (if applicable). Please contact us at +91 8130290915 | TOLL-FREE: 1800-889-1064 or at info@theindianpharma.com to buy Dobutamine from India at the best price.

Can I get Dobutamine 250 mg/5mL even if I am not based in India?

THE INDIAN PHARMA (TIP) helps patients access Dobutamine 250 mg/5mL, which is not approved in their home country, against a valid prescription and in conformity with their respective country’s local laws and regulations. Send your inquiry to find generic Dobutamine in UAE, Iraq, Iran, Argentina, Brazil, Chile, Colombia, Peru, Saudi Arabia, Jordan, Mexico, Venezuela, Romania, Switzerland, Georgia, Turkey, Italy, UK, Ukraine, Sri Lanka, Afghanistan, Poland, Slovakia, Armenia, Kazakhstan, Germany, Azerbaijan, Latvia, Moldova, the Philippines, Tajikistan, Turkmenistan, Uzbekistan, Mongolia, Algeria, Mauritius, Uganda, Zimbabwe, Australia, New Zealand, China, Cambodia, Indonesia, Malaysia, Singapore, Thailand, Vietnam, Kenya, Morocco, Belgium, Bulgaria, Bolivia, Somalia, Hong Kong, Mali, Cameroon, Nepal, Hungary, Papua New Guinea, Nigeria, Pakistan, Saint Kitts And Nevis, Tanzania, Panama, South Korea, Congo, Jamaica, Saint Lucia, Bahrain, Guyana, Malawi, Uruguay, Mozambique, Bangladesh, Ethiopia, Benin, Botswana, Ghana.

Where can I get the best Dobutamine Cost Price in India?

The price of Dobutamine 250 mg/5mL is low and reasonable in India compared to other countries. If you wish to buy Dobutamine online from India at an affordable price, contact us today. We will help facilitate the supply of this therapeutic drug at the lowest possible prices.

Is it safe to buy Dobutamine 250 mg/5mL online from India?

Yes, one can buy generic Dobutamine online at the best price from THE INDIAN PHARMA (TIP) if this drug is not registered or is unavailable in their country. TIP can help facilitate the supply/export of generic Dobutamine 250 mg/5mL through legal channels.

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