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Trodelvy (Sacituzumab govitecan-hziy)

Brand Name: Trodelvy
Innovator Brand Name: Trodelvy
API: Sacituzumab govitecan-hziy
Packaging: 1 Vial (Per Box)
Strength: 180mg lyophilized powder for injection
Manufacturer Name: Gilead Sciences, Inc.

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Description

Trodelvy (Sacituzumab govitecan-hziy) injection is a Trop-2-directed ADC and topoisomerase inhibitor conjugate approved to treat adults with:
  • Unresectable locally advanced or mTNBC (metastatic triple-negative breast cancer) who have previously been treated with two or more systemic therapies, at least one of them for metastatic disease.
  • Unresectable locally advanced or metastatic hormone receptor (HR)- positive, human epidermal growth factor receptor 2 (HER2)-negative (IHC 0, IHC 1+ or IHC 2+/ISH–) breast cancer who have been treated with endocrine-based therapy and at least two additional systemic therapies in the metastatic setting.
  • Locally advanced or metastatic urothelial cancer (mUC) who have previously been treated with platinum-containing chemo and either PD-1 (which stands for programmed death receptor-1) or PDL1 (which stands for programmed death-ligand 1 inhibitor).
Posology & Administration: The recommended dose of Trodelvy (Sacituzumab govitecan-hziy) injection is 10 mg/kg given as an IV infusion once a week on Days 1 & 8 of 21-day therapy cycles until disease progression or in case of unacceptable toxicity. Do not administer doses of Trodelvy more than 10 mg per kg. Trodelvy needs to be administered as an intravenous (IV) infusion only. Avoid administering as an intravenous (IV) push or bolus.  
  • First infusion: Administer intravenous (IV) infusion over three hours. Observe patients throughout the infusion and for at least 30 minutes after the initial dose to notice/see any sign or symptom of infusion-related reactions.
  • Subsequent infusions: Administer intravenous (IV) infusion over 1 to 2 hours if previous infusions were tolerated. Observe patients throughout the IV infusion and for at least 30 minutes following the IV infusion.

Important Safety Information

Interstitial Lung Disease (ILD) and Pneumonitis: Trodelvy can lead to severe or life-threatening ILD and pneumonitis. Patients should be closely monitored for any signs of respiratory symptoms, and treatment should be discontinued if ILD or pneumonitis is suspected.

Neutropenia: Trodelvy treatment may result in severe neutropenia, increasing the risk of infection. Regular monitoring of complete blood counts is essential, with appropriate dose adjustments or delays as required.

Diarrhea: Trodelvy can cause severe or life-threatening diarrhea. Patients should be monitored for diarrhea and dehydration, with prompt initiation of supportive care measures. Antidiarrheal agents and dose modifications may be necessary.

Hypersensitivity Reactions: Hypersensitivity reactions, including anaphylaxis, may occur with Trodelvy treatment. Patients should be monitored for signs and symptoms of hypersensitivity, and treatment should be discontinued if a reaction occurs.

Embryo-Fetal Toxicity: Trodelvy can cause fetal harm when administered to pregnant women. Pregnancy should be avoided during treatment, and effective contraception should be used in women of childbearing potential.

Hepatotoxicity: Trodelvy may result in hepatotoxicity, characterized by elevated liver enzymes and hepatic impairment. Regular monitoring of liver function tests is necessary, with treatment interruption or discontinuation as warranted.

Secondary Malignancies: Trodelvy treatment may increase the risk of developing secondary malignancies. Patients should be monitored for signs and symptoms of secondary malignancies, with appropriate diagnostic evaluations if malignancy is suspected.

Adverse Reactions: The most common adverse reactions (≥25%) associated with Trodelvy treatment include neutropenia, nausea, diarrhea, fatigue, anemia, vomiting, alopecia, constipation, decreased appetite, rash, and abdominal pain.

Documentation & Availability

What documents are required to import TRODELVY to India? TRODELVY (sacituzumab govitecan-hziy) injections can be imported by patients or government hospitals on the name of the patients only. The following documentation is needed to import the product:
  • A valid prescription from a qualified doctor.
  • Patients diagnostic reports
  • Patient ID proof (issued by the government of India)
How does the order be confirmed? The order will be confirmed only after the receipt of:
  • Valid prescription of Doctor
  • Import permit if applicable
Is TRODELVY available in India? TRODELVY (sacituzumab govitecan-hziy injection) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed. IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input
  • On availability of Trodelvy in India ( Kolkata, Hyderabad, Mumbai, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
  • Medicine Price.
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TRODELVY can be made available to patients, doctors, and hospitals in Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit. TIP (The Indian Pharma) can facilitate the supply of TRODELVY (prescription medicines) to all locations in the world and India after fulfilling the legal requirement (if applicable). Please contact +91-9310090915 | Toll-Free No: 1800-889-1064 or write us at info@theindianpharma.com for Trodelvy price in India. We guarantee quality and delivery in every corner of the world as per the buyer’s requirements.

Sourcing & Delivery

The Indian Pharma (TIP) can source TRODELVY (Cancer Treatment Medicines) from across the globe and has the ability to supply. TIP offers its customers worldwide access to the best available treatment. The Indian Pharma (TIP) has the potential to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

FAQ

What does Trodelvy contain as an active substance? Trodelvy specifically contains the active substance Sacituzumab govitecan-hziy.

How is Trodelvy supplied? Trodelvy is supplied for injection: 180 mg lyophilized powder in a single-dose vial for intravenous use. It is available by prescription only.

What are the common side effects of Trodelvy? Common side effects of Trodelvy may include neutropenia, nausea, diarrhea, fatigue, anemia, vomiting, alopecia, constipation, decreased appetite, rash, and abdominal pain.

How much does Trodelvy cost in India? Get the best Trodelvy cost in India. If you want to buy it online, then THE INDIAN PHARMA (TIP) can help you access this medicinal product at the most competitive price in India through legal channels.

How to store Trodelvy? Store vials of Trodelvy in a refrigerator at 2 to 8°C (36 to 46°F) in the original carton to protect them from the light until the time of reconstitution. It is not advisable to freeze this medicine.

Is the Trodelvy Injection Available In India? Trodelvy is an imported medicine that is not readily available in India. It can be imported against a valid prescription and import permit. THE INDIAN PHARMA (TIP) can facilitate the supply of Trodelvy 180 mg after fulfilling the legal requirement (if applicable). Please contact us via +919310090915 or TOLL-FREE: 1800-889-1064 or write to us at info@theindianpharma.com to buy Trodelvy online in India.

Can I get Trodelvy even if I am not based in India? THE INDIAN PHARMA (TIP) helps patients access/import Trodelvy (Sacituzumab govitecan-hziy), not approved in their home country against the valid prescription and in conformity with the local laws and regulations of their respective country.

Where can I get Trodelvy at the best price? To get the best Trodelvy injection price in India and other countries, always buy this medication from a Pharmaceutical Wholesaler Company that is GDP-certified. Noida-based THE INDIAN PHARMA (TIP) can offer the best price for Trodelvy (Sacituzumab govitecan-hziy).

Is it safe to buy Trodelvy online in India? Yes, one can buy Trodelvy online from India-based The Indian Pharma (TIP) if Trodelvy 180 mg is not registered or is unavailable in the country. We can facilitate the supply of Trodelvy injection through legal channels.

The Indian Pharma (TIP) has the potential to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

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