Description
Uses of medication: Sebelipase alfa is indicated in order to treat patients with a rare disease known as Lysosomal Acid Lipase (LAL) deficiency.
Dosage: Sebelipase alfa is given to you or your child by an infusion (drip) into a vein. The drug will be diluted prior to being given to you or your child. Each infusion will generally take approximately 1-2 hours. You or your child may be monitored by your healthcare practitioner for an additional hour following the infusion. For infants patients (< 6 months of age), the recommended starting dose is 1 mg/kg once weekly. For children and adults, the recommended dose is 1 mg per kg body weight once every other week.
Treatment Reactions: The most commonly reported sebelipase alfa side effects may include:
- Diarrhea
- Vomiting
- Fever
- Rhinitis
- Anemia
- Cough
- Nasopharyngitis
- Urticaria
- Headache
- Oropharyngeal
- Pain
- Asthenia
- Constipation
- Nausea
Warnings and Precautions:
- While on sebelipase alfa 10 ml vial, if you/your child have severe infusion reactions, seek immediate medical assistance.
- In cases of severe infusion reactions and in cases of lack or loss of effect, patients need to be tested for the existence of antibodies.
- Sebelipase may be responsible for having a minor influence on the ability to drive as well as use machines. Dizziness has been reported with the use of sebelipase alfa 20 mg which could affect the ability to drive/use machines.
- In case you’re pregnant or breast-feeding, think you may be pregnant or are planning to conceive a baby, ask your healthcare provider for advice prior to taking this drug.
- Development of blood proteins against kanuma 20 mg, also named anti-drug antibodies, may occur while on treatment. Talk to your healthcare practitioner in case you have reduced efficacy with this drug.
- This medication may contain egg proteins. In case you/your child has an egg allergy or a history of allergies to eggs, inform your healthcare provider.
