Cabozantinib Tablets

Facts of Medicine

  • Innovator Name- Cabometyx
  • Medicine Name- Cabotres
  • API- Cabozantinib
  • Packaging- 30 Tablets
  • Strength- 20 mg and 40 mg
  • Manufactured by- Cipla
Get Price


Cabozantinib Uses:

Cabozantinib is a kinase inhibitor used for the treatment of

  • patients with advanced renal cell carcinoma (RCC).
  • patients with advanced RCC, as a first-line treatment along with nivolumab.
  • patients with hepatocellular carcinoma (HCC) who have been previously taken treatment with sorafenib.


The recommended dosage of Cabozantinib as a single agent for Renal Cell Carcinoma and Hepatocellular Carcinoma is 60 mg orally, once daily without food until disease progression or unacceptable toxicity.

The recommended dosage of Cabozantinib for Renal Cell Carcinoma (RCC) is 40 mg orally, once daily, administered in combination with nivolumab 240 mg every 2 weeks or 480 mg every 4 weeks. Do not administer Cabozantinib with food. Administer at least 60 minutes prior to or at least 120 minutes after eating. Swallow Cabozantinib tablets whole without crushing. Do not take the missed dose within 12 hours of the next scheduled dose. Do not substitute tablets of Cabozantinib with Cabozantinib capsules. Stop Cabozantinib treatment at least 3 weeks prior to scheduled surgery, including dental surgery.

Side Effects:

The most commonly reported side effects are:

as a single agent: fatigue, diarrhea, decreased appetite, PPE, nausea, vomiting, hypertension, weight decreased, constipation, dysphonia.

in combination with nivolumab: diarrhea, hepatotoxicity, PPE, fatigue, stomatitis, hypertension, hypothyroidism, musculoskeletal pain, rash, decreased appetite, nausea, dysgeusia, cough, abdominal pain, and upper respiratory tract infection.

Warnings and Precautions:
  • Severe and fatal hemorrhages occurred with Cabozantinib. The incidence of Grade 3-5 hemorrhagic events was noted in Cabozantinib-treated patients in RCC and HCC studies. Discontinue treatment for Grade 3/4 hemorrhage. Avoid administering it to patients who have a known history of hemorrhage, including hematemesis, hemoptysis, or melena.
  • Fistulas, Gastrointestinal perforations, including fatal cases, occurred in Cabozantinib-treated patients. Monitor patients for signs/symptoms of fistulas and perforations, including abscess and sepsis. Discontinue treatment in patients who experience a Grade-4 fistula or a Gastrointestinal perforation. 
  • Cabozantinib can cause hypertension, including hypertensive crisis. Hypertension was reported in Cabozantinib-treated patients. Do not initiate the treatment in patients with uncontrolled hypertension. Monitor blood pressure on a regular basis during treatment. 
  • Diarrhea occurred in patients treated with this medicine. Withhold treatment until improvement to Grade-1 and resume treatment at a reduced dose for intolerable Grade-2 diarrhea, Grade-3 diarrhea that cannot be managed with standard anti diarrheal treatments, or Grade-4 diarrhea. 
  • Cabozantinib along with nivolumab can cause hepatotoxicity with higher frequencies of Grades 3/4 ALT/AST elevations compared to Cabozantinib alone. Monitor liver enzymes before initiation of and throughout treatment. Consider frequent monitoring of liver enzymes as compared to when the medicines are administered as single agents.
  • Proteinuria was noted in 7 percent of patients receiving this medicinal product. Monitor urine protein on a regular basis during treatment. Discontinue this medicine in those patients who develop nephrotic syndrome. 
  • Wound complications occurred with Cabotres Tablet. Withhold treatment for at least 3 weeks prior to elective surgery. Avoid administering this medication for at least two weeks after major surgery and until adequate wound healing. 
  • Treatment with cabozantinib can cause fetal harm if used by a pregnant woman. Instruct pregnant women of the potential risk to a fetus. Instruct females of reproductive age to use effective contraception during treatment and for 4 months after the last dose.

More Info


Store Cabozantinib at 20 to 25°C (68 to 77°F); excursions are permitted from 15 to 30°C (59 to 86°F). Keep Cabozantinib and all medicines out of the reach of children.

Availability in India:

The Indian Pharma helps connect buyers with suppliers who can ship Cabozantinib at the global level as per the needs of buyer’s. The Indian Pharma provides guarantee of quality and delivery for the Cabozantinib Tablets.

Buying Procedure:

In order to buy Cabozantinib, you can contact us at our Toll-free number 1800 889 1064 or on WhatsApp Number +91 8130290915 or an Email to us at: along with your Proof of Identity, Valid Prescription Letter and Medical Reports.


In conclusion, treatment with cabozantinib, a TKI that targets MET, VEGF receptors, and AXL, resulted in increased overall survival and progression-free survival than placebo in patients with earlier treated advanced hepatocellular carcinoma and renal cell carcinoma (RCC).


Is Cabozantinib a chemotherapy medicine?

Cabozantinib is also known by the brand names Cometriq or Cabometyx. This is a chemotherapy medication.

What class of drug is Cabozantinib?

Cabozantinib is in a class of medications named tyrosine kinase inhibitors.

How much does Cabozantinib cost?

The cabozantinib cost in India is reasonable and can vary. To procure it authentically, you can get in touch with us either via TOLL-FREE: 1800 889 1064 or WhatsApp: +91 8130290915 or Email:

Where can I get Cabozantinib at the best price?

In order to get the best cabozantinib price in India, always buy this medication from a Pharmaceutical Wholesaler Company which is certified by the higher authorities like WHO-GDP & ISO 9001:2008.

Can I get Cabozantinib even if I am not based in India?

The Indian Pharma helps patients in accessing or importing Cabozantinib, not approved in their home country against the legitimate prescription and in conformity with the all local laws and regulations of their home country.

Is it safe to buy Cabozantinib online in India?

Yes, You can buy cabozantinib from India online from if this medicinal product is not available or has not been approved in your country.