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Sorafenib 200 mg tablets

Facts of Sorafenib

  • API: Sorafenib
  • Packaging & Strength: Tablets: 200 mg
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Description

Uses of Medicine:

Sorafenib 200 mg tablets fall under the anti-cancer group of medicines. This kinase inhibitor is supplied generically as well as in branded medicine. Patients, Healthcare Professionals (HCPs), or Hospitals can buy Sorafenib 200 mg tablets online from India through THE INDIAN PHARMA (a trusted Sorafenib Supplier, Exporter, and Contract Manufacturer in India) for the management and treatment of adult patients with:
  • Unresectable Hepatocellular Carcinoma (HCC)
  • Advanced Renal Cell Carcinoma (RCC)
  • Locally Recurrent or Metastatic, Progressive, Differentiated Thyroid Carcinoma (DTC) Refractory to Radioactive Iodine Treatment
 

Sorafenib 200 mg is formulated as a targeted therapy. It is widely used to treat advanced renal cell carcinoma (kidney cancer), hepatocellular carcinoma (liver cancer), and differentiated thyroid carcinoma (thyroid cancer) in those who do not respond to radioactive iodine therapy. This oral therapeutic drug works by blocking the progression of unhealthy cells and cutting off the blood supply to tumors. Sorafenib 200 mg is usually prescribed when surgery is not an option. It is taken orally as per the doctor’s prescription. Do not stop treatment without medical advice.

Some patients, while on this treatment, may experience low blood calcium levels. In case this becomes severe or does not go away, consult your healthcare provider (HCP). It is important to stay hydrated and eat a balanced diet to manage these side effects. If any unusual symptoms, such as severe bleeding or heart problems, occur, seek medical help immediately.

Before starting treatment with Sorafenib 200 mg tablets, let your doctor know if you have heart disease, chest pain, high blood pressure, or bleeding disorders. Do not take this medicine if you are allergic to its ingredients. If you are undergoing surgery or have recently had one, let your doctor know, as Sorafenib 200 mg may affect wound healing. Women should use effective contraception during treatment and for 6 months after the final dose, while men should continue contraception for 3 months after the final dose. Always follow your doctor’s instructions for safe and effective use of Sorafenib.

Dosage & Side Effects: 

Dose for Hepatocellular Carcinoma, Renal Cell Carcinoma, and Differentiated Thyroid Carcinoma: The recommended daily dose of Sorafenib is 400 mg (2 x 200 mg tablets) taken twice daily without food (at least 60 minutes before or 120 minutes after a meal). Treatment should continue until the patient is no longer clinically benefiting from therapy or until there is evidence of unacceptable toxicity.

When dose reduction is necessary, the dose of Sorafenib may be reduced to 400 mg once daily. If additional dose reduction is required, Sorafenib may be reduced to a single 400 mg dose every other day.

The most common side effects of Sorafenib 200 mg are diarrhea, alopecia, fatigue, infection, decreased appetite, hand-foot skin reaction, rash, nausea, gastrointestinal and abdominal pains, weight loss, hypertension, and hemorrhage.

Warning and Precautions

  • There is a likelihood of an increase of cardiovascular events such as ischemic heart disease and myocardial infarction occurring with the use of Sorafenib 200 mg tablets. These patients will likely require closer attention. Cardiac events must be closely monitored, and therapy should be suspended upon the occurrence of severe symptoms. Consistent evaluations of the heart via ECGs need to be done alongside the treatment plan.
  • Reported uses of this medicine have occurred with adverse effects such as bleeding, including gastrointestinal bleeding. Be careful when treating patients with active bleeding or those on blood thinners. Be on the lookout for black colored stools, vomiting of blood, or unexplainable bruises. In life-threatening cases, medication must be withdrawn.
  • Hypertension is reported as a side effect from the use of this drug. It is important to track blood pressure frequently. In cases where this medicine is combined with other drugs that increase blood pressure, antihypertensive treatment will need to be employed. Dosage must be lowered or changed in cases of uncontrolled severe hypertension. Active hypertension must be controlled expertly before treatment begins.
  • Reactions of skin on palms and soles of feet to topical treatments can hurt and cause skin rashes as well as redness of skin locally. More severe cases might require the medication to be stopped or for the dosage to be lowered. Assist patients with how they can care for their skin post and prevent excessive heat or friction to the area. Mild to moderate symptoms, topical lotions for management.
  • There have been reports of perforations of the GI tract that can be lethal. Watch for extreme pain in the abdomen, vomiting, and signs of abdominal infection. Those with risk factors like previous surgery on the abdomen should be evaluated carefully. Stop the treatment in cases of GI tract perforation.
  • Arrhythmia or sudden cardiac arrest can result from prolonged QT intervals caused by this treatment. Thus, monitoring electrolyte levels is critical, and anticipating drug interactions with other QT prolonging agents is important. Patients suffering from preexisting cardiac abnormalities need stringent cardiac supervision during therapy.
  • Regular monitoring of liver function is imperative owing to the possibility of severe hepatic toxic effects, including, but not limited to, hepatic failure. Caution is required in those with underlying liver disease. Significant elevations of liver enzymes and anicteric jaundice need discontinuation of therapy as these indicate serious hepatotoxic actions of this therapeutic drug.
  • Sorafenib may interfere with thyroid hormone suppression therapy in differentiated thyroid carcinoma (DTC). Close monitoring of TSH with dose adjustment of levothyroxine is the best approach. Careful management is required in those suffering from underactive thyroid to ensure adequate suppression of TSH is achieved.
  • Like other anti-neoplastic drugs, Sorafenib 200 mg has the potential to inflict damage to the fetus if taken during pregnancy. Women capable of becoming pregnant should be placed on effective contraception during treatment and, preferably, up to six months after stopping the drug. Those who do become pregnant need to be counseled on the risks the drug may inflict on fetal development.

FAQ's

What is Sorafenib?

Sorafenib is a generic medicine. It is commonly available in 200 mg Tablets and is primarily used for the treatment of Hepatocellular Carcinoma (HCC), Renal Cell Carcinoma (RCC), and Differentiated Thyroid Carcinoma (DTC).

How is the Sorafenib supplied?

Sorafenib is supplied in the form of 200 mg Tablets for oral administration. This medicine is commonly used for treating liver, kidney, and thyroid cancers.

How much does a Sorafenib 200 mg Tablet cost?

Please call/WhatsApp +91 8130290915 or dial our TOLL-FREE Number 1800-889-1064 to know the best Sorafenib 200 mg Tablets cost in India. If you want to buy Sorafenib online, then THE INDIAN PHARMA (TIP) can help you access this medicinal product at the most competitive price through legal channels.

Are Sorafenib 200 mg Tablets available in India?

Sorafenib is a pharmaceutical prescription medicinal product that can only be dispensed with a valid prescription from a treating physician. THE INDIAN PHARMA (TIP) can facilitate the supply of this drug to all locations after fulfilling the legal requirements (if applicable). Please contact us at +91 8130290915 | TOLL-FREE: 1800-889-1064 or at info@theindianpharma.com to buy generic Sorafenib 200 mg Tablets from India at the best price.

Can I get Sorafenib 200 mg Tablets even if I am not based in India?

THE INDIAN PHARMA (TIP) helps patients access Sorafenib 200 mg Tablets, which are not approved in their home country, against a valid prescription and in conformity with their respective country’s local laws and regulations.

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Where can I buy Sorafenib 200 mg Tablets from a Trusted Supplier?

You can buy Sorafenib 200 mg Tablets online from India through a trusted generic medicine supplier, exporter, and contract manufacturer like THE INDIAN PHARMA (TIP). We are known for offering high-quality, affordable, and low-priced medicines. Contact us today for more information on availability and pricing.

Where can I get the best Sorafenib 200 mg Tablets Cost Price in India?

The price of Sorafenib 200 mg Tablets is low and reasonable in India compared to other countries. If you wish to buy Sorafenib online from India at an affordable price, contact us today. As trusted pharmaceutical wholesale distributors in India, we will help facilitate the legal supply of this therapeutic drug at the lowest possible prices.

Is it safe to buy Sorafenib 200 mg Tablets online from India?

Yes, one can buy Sorafenib 200 mg Tablets online at the best price from THE INDIAN PHARMA (TIP) if this drug is not registered or is unavailable in their country. TIP can help facilitate the supply of generic Sorafenib Tablets through legal channels.
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