The Indian Pharma

Foscavir (Foscarnet sodium hexahydrate)

  • Medicine Name: Foscarnet  
  • API: Foscarnet Sodium
  • Packaging & Strength: Vials of 25 mL
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Description

Uses of Medicine:

Foscarnet 24 mg/mL injection is an antiviral therapeutic drug. It prevents certain viruses from multiplying in the body. Patients, Healthcare Professionals (HCP), or Hospitals can buy Foscarnet 24 mg/mL Injections online from India through THE INDIAN PHARMA (a trusted Foscarnet Supplier, Exporter, and Contract Manufacturer in India) for the treatment of
    • CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS).
    •  Acyclovir-resistant mucocutaneous HSV infections in immunocompromised patients.

Foscarnet 24 mg/mL injection is a prescription medicine. It is widely used for the treatment of serious viral infections, particularly in individuals with weakened immune systems, such as those living with AIDS.

Foscarnet is mainly used to treat a virus known as cytomegalovirus (CMV). CMV can cause a very serious eye infection called CMV retinitis, which may cause vision complications or even blindness. The medicine is especially useful for individuals who cannot take another common CMV medicine called ganciclovir, either because they have side effects from it or because it is no longer effective for them. In such scenarios, Foscarnet 24 mg/mL injection works as a backup treatment, often known as salvage therapy.

This therapeutic drug is also used for the treatment of herpes simplex virus (HSV) infections. It is especially used in those whose immune systems are weak. HSV usually causes cold sores or genital sores. Most individuals respond well to a medicine known as acyclovir, which is considered the standard treatment. But sometimes, the virus becomes resistant to acyclovir, which means the medicine no longer works. In these scenarios, Foscarnet injection can be used as an alternative treatment.

The medicine is usually administered through an IV (intravenous infusion), which means it goes directly into a vein. Because it’s a strong therapeutic drug, it is typically used in a hospital or under close medical supervision.

In summary, Foscarnet 24 mg/mL injection is an important antiviral medicine used when other treatments don’t work or can’t be considered. This treatment helps manage life-threatening infections caused by CMV and HSV in individuals with weakened immune systems and plays an important role in preventing further complications from these viral diseases.

Dosage & Side Effects:

CMV Retinitis (Induction Therapy): The recommended dosage of Foscarnet for induction therapy is 60 mg/kg every 8 hours or 90 mg/kg every 12 hours, administered as an intravenous (IV) infusion over 2 hours for 14 to 21 days.  Maintenance Therapy (CMV Retinitis): After the induction phase, patients typically continue with maintenance therapy at a dose of 90 to 120 mg/kg once daily, administered as an IV infusion over 2 hours to prevent disease progression. Acyclovir-Resistant HSV Infections: The recommended dosage for acyclovir-resistant mucocutaneous HSV infections is 40 mg/kg IV every 8 hours over at least 1 hour, typically continued for 2 to 3 weeks or until clinical resolution is observed.

Staying well-hydrated before and during Foscarnet treatment is important; doing so lowers the chance of kidney damage. Generally, a quick drip of 750 to 1000 mL of normal saline or dextrose-saline is given just before the drug starts.

Because Foscarnet is hard on the kidneys, doses must be cut in patients with poor kidney function, and doctors should check serum creatinine regularly. Because the drug has a narrow safety margin and can cause serious side effects, it should only be given by healthcare providers who specialize in antiviral therapy.

The most common side effects of Foscarnet injection are fever, flu-like symptoms, nausea, vomiting, diarrhea, chest pain, back pain, or headache.

Warning and Precautions

  • Foscarnet treatment can harm the kidneys. Monitor kidney function before and throughout the treatment. Dosage can be reduced for patients with kidney complications. Ensure adequate hydration to reduce the risk. Stop treatment in case serious kidney damage arises. Do not use other kidney-toxic medicines along with Foscarnet 24 mg/mL injection unless absolutely necessary.
  • Treatment with this medicine may cause imbalances in magnesium, calcium, potassium, and phosphorus. Check blood levels continuously during treatment. Imbalances may cause serious complications like irregular heartbeats or seizures. Correct any abnormal levels promptly. Use precisely in those prone to electrolyte disturbances or malnutrition.
  • Foscarnet can cause seizures, especially if calcium or other electrolytes are low. Monitor neurological status and correct imbalances promptly. Use caution in patients with a seizure history. Stop treatment quickly in case seizures occur and assess electrolyte levels and medicine concentration.
  • This therapeutic drug may cause allergic reactions, including fever, skin rashes, and rarely, serious reactions like anaphylaxis. Stop therapy in case signs of hypersensitivity arise. Avoid re-exposure to treatment in affected patients. Let patients know about symptoms like rash, itching, or breathing difficulty and seek assistance quickly.
  • Treatment with Foscarnet injection may cause alterations in heart rhythm, including QT prolongation and torsade de pointes. Monitor ECG in those who are high-risk patients. Do not use with other QT-prolonging medicines. Electrolyte abnormalities must be corrected. Stop therapy in case significant changes in heart rhythm or signs of arrhythmia arise.
  • Therapy with Foscarnet 24 mg/mL injection can irritate the injection site, including redness, pain, or swelling. Use appropriate vein access and infusion rate. Try to rotate injection sites. Stop infusion in case serious reactions occur. Inform the healthcare provider immediately if discomfort continues or worsens during treatment.
  • This treatment may lower blood cell counts, causing leukopenia, anemia, or thrombocytopenia. Monitor blood counts continuously during treatment. Stop or adjust treatment if levels drop significantly. Use cautiously in patients with pre-existing blood disorders or receiving other bone marrow-suppressing medicines simultaneously.
  • This medicine contains high sodium levels, which may worsen conditions such as high blood pressure, heart failure, or kidney disease. Monitor fluid and sodium levels precisely. Consider low-sodium alternatives for at-risk patients. Alert patients on sodium-restricted diets so they understand the extra salt they are getting each day.
  • Foscarnet injection should be used in pregnancy only if absolutely required. Animal studies hint at fetal harm, but the data are unclear. Well-controlled human trials have never been run, so the true risk remains unknown. Talk openly with the pregnant patient about what the studies show and about her own health. Do not use during pregnancy unless the benefits clearly outweigh the potential harm to the unborn baby.
  • It is not known whether this medicine passes into breast milk. Because of the potential serious side effects in nursing infants, avoid breastfeeding while using Foscarnet. Decide together with the mother to stop either the drug or nursing, weighing how crucial the treatment is for her and how much risk that poses for the baby.

FAQ

What is Foscarnet?

Foscarnet is an antiviral medicine. It is widely used for the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS). The medicine is also used for the treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised patients.

How is Foscarnet supplied?

Foscarnet is supplied for Intravenous (IV) Infusion Solution, 24 mg/mL in a 250 mL glass bottle.

How much does a Foscarnet 24 mg/mL Injection cost?

Please call/WhatsApp +91 8130290915 or dial our TOLL-FREE Number 1800-889-1064 to know the best Foscarnet 24 mg/mL Injections cost in India. If you want to buy Foscarnet online, then THE INDIAN PHARMA (TIP) can help you access this medicinal product at the most competitive price through legal channels.

Are Foscarnet 24 mg/mL Injections available in India?

Foscarnet is a pharmaceutical prescription medicinal product that can only be dispensed with a valid prescription from a treating physician. THE INDIAN PHARMA (TIP) can facilitate the supply of this drug to all locations after fulfilling the legal requirements (if applicable). Please contact us at +91 8130290915 | TOLL-FREE: 1800-889-1064 or at info@theindianpharma.com to buy generic Foscarnet Injections from India at the best price.

Can I get Foscarnet 24 mg/mL Injections even if I am not based in India?

THE INDIAN PHARMA (TIP) helps patients access Foscarnet Injections, which are not approved in their home country, against a valid prescription and in conformity with their respective country’s local laws and regulations.

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Where can I buy Foscarnet 24 mg/mL Injections from a Trusted Supplier?

You can buy Foscarnet 24 mg/mL Injections online from India through a trusted generic medicine supplier, exporter, and contract manufacturer like THE INDIAN PHARMA (TIP). We are known for offering high-quality, affordable, and low-priced medicines. Contact us today for more information on Foscarnet availability and pricing.

Where can I get the best cost-price for Foscarnet 24 mg/mL Injections in India?

The price of Foscarnet 24 mg/mL Injections is low and reasonable in India compared to other countries. If you wish to buy Foscarnet online from India at an affordable price, contact us today. As trusted pharmaceutical wholesale distributors in India, we will help facilitate the legal supply of this therapeutic drug at the lowest possible prices.

Is it safe to buy Foscarnet 24 mg/mL Injections online from India?

Yes, one can buy Foscarnet 24 mg/mL Injections online at the best price from THE INDIAN PHARMA (TIP) if this drug is not registered or is unavailable in their country. TIP can help facilitate the supply of generic Foscarnet Injections through legal channels.
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