What is CLOFARABINE?

Clofarabine injection is a purine nucleoside metabolic inhibitor indicated for the treatment of pediatric patients 1 to 21 years old with relapsed or refractory acute lymphoblastic leukemia after at least two prior regimens.

Dosage: The recommended pediatric dose of 52 mg/m2 should be administered as an intravenous infusion over 2 hours daily for 5 consecutive days of one month (28­ days) cycle. The treatment cycles should be repeated each 2 to 6 weeks.

Treatment Reactions: The most commonly observed clofarabine side effects may include:

  • Rash
  • Nausea
  • Febrile
  • Pyrexia
  • Fatigue
  • Anxiety
  • Pruritus
  • Flushing
  • Vomiting
  • Diarrhea
  • Headache
  • Neutropenia
  • Mucosal inflammation
  • Palmar-plantar erythrodysesthesia syndrome

In case you have any unusual side effects due to clofarabine 20 mg, report your healthcare practitioner right away.