Crizalk — Crizotinib
Crizotinib was among the first targeted therapies to demonstrate that lung cancer isn't a single disease but a collection of genetically distinct subtypes — it works only in patients whose tumors carry specific ALK or ROS1 gene rearrangements, which means biomarker testing at the receiving facility isn't optional, it's a hard prerequisite that directly determines whether this drug will help a given patient at all.
- Approved indications: ALK-positive or ROS1-positive non-small cell lung cancer (NSCLC)
- Mechanism: Inhibits ALK and ROS1 tyrosine kinases, blocking the abnormal growth signaling these gene rearrangements drive in tumor cells
- Prescribing prerequisite: Confirmed ALK or ROS1 positivity via molecular/genetic testing is required before starting — a key procurement-planning consideration for distributors evaluating whether a receiving facility has adequate diagnostic capability
- Administration: Oral capsule, typically twice daily
Key Product Facts
200 mg, 250 mg
Strength
60 Capsule (S) In A Box
Pack Size
Crizotinib
Active Ingredient
Oncology
Category
Enquire Now for Pricing
Price
Crizotinib was among the first targeted therapies to demonstrate that lung cancer isn't a single disease but a collection of genetically distinct subtypes — it works only in patients whose tumors carry specific ALK or ROS1 gene rearrangements, which means biomarker testing at the receiving facility isn't optional, it's a hard prerequisite that directly determines whether this drug will help a given patient at all.
- Approved indications: ALK-positive or ROS1-positive non-small cell lung cancer (NSCLC)
- Mechanism: Inhibits ALK and ROS1 tyrosine kinases, blocking the abnormal growth signaling these gene rearrangements drive in tumor cells
- Prescribing prerequisite: Confirmed ALK or ROS1 positivity via molecular/genetic testing is required before starting — a key procurement-planning consideration for distributors evaluating whether a receiving facility has adequate diagnostic capability
- Administration: Oral capsule, typically twice daily
- Vision disturbances: A very common side effect, usually mild, but patients should be counseled to expect it
- QT prolongation: A cardiac risk requiring ECG monitoring, particularly in patients with existing heart rhythm concerns
- Hepatotoxicity: Regular liver function monitoring recommended
- Interstitial lung disease: A rare but serious risk requiring immediate discontinuation if respiratory symptoms develop
- Pregnancy: Contraindicated
| Document |
Included |
| Certificate of Analysis (COA) |
Standard |
| Certificate of Origin (COO) |
Standard |
| MSDS |
Standard |
Stock status: Available on request | Quote turnaround: 24 hours
- Logistics: Standard export logistics, no cold chain required
- Coverage: Global export markets
- Tracking: Full shipment tracking included
What is Crizotinib used for?
Treats ALK-positive or ROS1-positive non-small cell lung cancer.
Get Crizotinib price from a GMP-compliant Indian supplier — how?
Send strength and destination for a verified quote.
Does it work for all lung cancer patients?
No, only patients with confirmed ALK or ROS1 gene rearrangements respond — genetic testing is required before treatment.
Who supplies Crizotinib from India?
WHO-GMP certified capsule manufacturing with full export documentation.
What are the common side effects?
Vision disturbances are very common, usually mild, alongside potential liver and cardiac monitoring needs.
