Lasinone — Nitisinone
Nitisinone treats hereditary tyrosinemia type 1, an ultra-rare inherited metabolic disorder that typically presents in infancy — the disease population is so small and dispersed globally that reliable, uninterrupted sourcing genuinely matters more to the pediatric metabolic specialists who prescribe it than price competitiveness, similar in profile to Mitotane in our catalogue, since patients on this therapy generally need it for life.
- Approved indication: Hereditary tyrosinemia type 1 (HT-1), a rare genetic disorder affecting the body's ability to break down the amino acid tyrosine
- Mechanism: Inhibits an enzyme in the tyrosine degradation pathway, preventing the buildup of toxic intermediate compounds that cause liver, kidney, and neurological damage in untreated patients
- Treatment duration: Typically lifelong from diagnosis, usually made in infancy or early childhood
- Buyer profile: Specialist pediatric metabolic-disease centers and inherited-disorder clinics — a narrow but globally consistent institutional buyer base
Key Product Facts
2 mg, 5 mg, 10 mg
Strength
60 Capsule (S) In A Bottle
Pack Size
Nitisinone
Active Ingredient
Endocrinology
Category
Enquire Now for Pricing
Price
Nitisinone treats hereditary tyrosinemia type 1, an ultra-rare inherited metabolic disorder that typically presents in infancy — the disease population is so small and dispersed globally that reliable, uninterrupted sourcing genuinely matters more to the pediatric metabolic specialists who prescribe it than price competitiveness, similar in profile to Mitotane in our catalogue, since patients on this therapy generally need it for life.
- Approved indication: Hereditary tyrosinemia type 1 (HT-1), a rare genetic disorder affecting the body's ability to break down the amino acid tyrosine
- Mechanism: Inhibits an enzyme in the tyrosine degradation pathway, preventing the buildup of toxic intermediate compounds that cause liver, kidney, and neurological damage in untreated patients
- Treatment duration: Typically lifelong from diagnosis, usually made in infancy or early childhood
- Buyer profile: Specialist pediatric metabolic-disease centers and inherited-disorder clinics — a narrow but globally consistent institutional buyer base
- Dietary requirement: Must be combined with strict dietary restriction of tyrosine and phenylalanine — coordination with a metabolic dietitian is essential alongside medication, not optional
- Ophthalmologic monitoring: Recommended given a known risk of corneal deposits affecting vision if tyrosine levels aren't well controlled
- Liver function monitoring: Required regularly, given the disease's own underlying hepatic risk alongside any medication-related considerations
- Discontinuation risk: Stopping treatment can lead to rapid recurrence of toxic metabolite buildup — supply continuity is a genuine clinical concern, not just a commercial one
| Document |
Included |
| Certificate of Analysis (COA) |
Standard |
| Certificate of Origin (COO) |
Standard |
| MSDS |
Standard |
| CTD/ACTD Dossier |
Available on request, relevant for named-patient import pathways |
Stock status: Available on request | Quote turnaround: Confirm strength and destination for pricing
- Logistics: Standard export logistics, no cold chain required
- Coverage: Global, serving a small but consistent set of specialist pediatric metabolic centers
- Tracking: Full shipment tracking included
What is Nitisinone used for?
Treats hereditary tyrosinemia type 1, a rare inherited metabolic disorder, usually diagnosed in infancy.
Get Nitisinone price from a GMP-compliant Indian supplier — how?
Send strength and destination for a verified quote.
Does it require dietary changes too?
Yes, treatment must be combined with strict dietary restriction of tyrosine and phenylalanine, managed alongside a metabolic dietitian.
Is it a lifelong treatment?
Yes, treatment is typically continued for life once diagnosed.
Who supplies Nitisinone from India?
WHO-GMP certified manufacturing with a focus on long-term supply continuity for pediatric patients.
