What is Triokris (Trientine Hydrochloride 250mg) used for?
Triokris is a copper-chelating agent used to treat Wilson's disease, a genetic disorder that causes toxic copper buildup in the liver, brain, and other organs. It is the standard second-line treatment for patients who cannot tolerate penicillamine.

How does it work?
Trientine binds to excess copper in the body, allowing it to be safely excreted through urine — preventing further organ damage and helping restore copper balance over time.

Who should take it?

• Patients diagnosed with Wilson's disease
• Patients intolerant or allergic to D-penicillamine
• Patients requiring long-term, ongoing chelation therapy (this is a lifelong treatment)

Dosage: As directed by the prescribing physician, based on individual copper levels and clinical response. This is a Schedule H prescription drug — not to be sold without a valid prescription.

• Swallow capsules whole. Do not chew or crush.
• Keep out of reach of children.
• Schedule H drug: available only against a Registered Medical Practitioner's prescription.
• Rare but serious side effects may include allergic reaction or anemia — seek immediate medical attention for rash, breathing difficulty, or unusual fatigue.
• Use during pregnancy only under direct medical supervision.
• Patients are generally advised to limit copper-rich foods (shellfish, nuts, chocolate, mushrooms, organ meats) to support treatment effectiveness.
• Inform your physician of all other medications/supplements, as some may interfere with absorption.

Regulatory documents provided with export orders:

• WHO-GMP / EU-GMP Certificates
• Certificate of Pharmaceutical Product (COPP)
• Certificate of Analysis (COA) — batch-specific
• Free Sale Certificate
• MSDS (Material Safety Data Sheet)
• Patient Information Leaflet (PIL)
• CTD/ACTD dossiers for market registration

Availability: In stock for export. Minimum order quantities are flexible and negotiable for licensed distributors, importers, hospitals, and NGOs.

Ikris Pharma Network exports Triokris to 200+ countries through a WHO-GDP-compliant, temperature-controlled logistics network (air and sea freight), ensuring product stability from dispatch to delivery.

Key export regions:

• LATAM: Brazil, Mexico, Colombia, Argentina, Chile, Peru, Ecuador, Bolivia, and others
• GCC/Middle East: UAE, Saudi Arabia, Qatar, Kuwait, Bahrain, Oman, Jordan, Iraq
• Africa: Nigeria, Kenya, Ghana, South Africa, Uganda, Tanzania, Ethiopia
• Asia & Europe: Vietnam, Philippines, Myanmar, UK, Germany, France, Italy (subject to local regulatory approval)

Direct sourcing is available for small and mid-sized distributors, with dedicated support for registration, documentation, and shipment tracking.

What is Triokris (Trientine 250mg) used for?

It treats Wilson's disease by binding excess copper and helping the body eliminate it through urine, preventing damage to the liver, brain, and other organs.

Can it be used if I'm allergic to penicillamine?

Yes. Trientine is the recommended alternative for patients who cannot tolerate or are allergic to penicillamine.

How should Triokris be stored?

Below 25°C, in a dry, dark place, protected from light and moisture.

What is the usual dose?

Dosage is individualized by the prescribing physician based on the patient's copper levels and clinical response.

Are there serious side effects?

Rare, but may include allergic reactions or anemia. Seek medical attention for rash, breathing difficulty, or fatigue.