Mitotane occupies a genuinely singular position in oncology — it's the only medicine specifically approved for adrenocortical carcinoma, an extremely rare cancer of the adrenal gland, which means there's no real alternative therapy for physicians to fall back on if a reliable supply isn't available. Because the patient population is so small and geographically scattered, most buyers sourcing this drug are specialist endocrine-oncology centers rather than general hospitals, and sourcing reliability tends to matter far more to them than price competitiveness.

• Approved indication: Adrenocortical carcinoma (adrenal cortex cancer), both as adjuvant therapy after surgery and for inoperable, recurrent, or metastatic disease
• Mechanism: Selectively cytotoxic to adrenal cortex cells, causing adrenal tissue destruction and suppressing steroid hormone production from tumor cells
• Treatment duration: Often continued for months to years, requiring consistent long-term supply rather than a single course
• Buyer profile: Specialist endocrine-oncology centers and university hospital cancer programs — a narrow but consistent institutional buyer base globally, given how rare this cancer is

Because Mitotane destroys adrenal tissue as part of its mechanism, it inevitably causes adrenal insufficiency in the patient — meaning treatment isn't just about giving the drug, but managing the hormone-replacement therapy that has to run alongside it under close endocrinology supervision.

• Adrenal insufficiency: Expected and requires steroid replacement therapy (hydrocortisone) with dose titration managed by an endocrinologist throughout treatment
• Neurotoxicity: Can occur at higher doses — symptoms include dizziness, lethargy, and confusion, requiring dose adjustment if they appear
• Pregnancy: Strictly contraindicated — severe, well-documented teratogenicity risk
• Drug level monitoring: Blood mitotane levels are typically monitored periodically to guide dosing and avoid toxicity
• Hepatic function: Regular liver function monitoring recommended given known hepatotoxicity risk

Stock status: On request | Quote turnaround: Confirm quantity and destination for pricing

• Logistics: Standard export logistics — room-temperature stable, no cold chain required
• Coverage: Global, serving a small but geographically dispersed set of specialist centers
• Tracking: Full shipment tracking included

What is Mitotane used for?

It treats adrenocortical carcinoma, a rare cancer of the adrenal gland, and is the only medicine specifically approved for this condition.

Get Mitotane price from a GMP-compliant Indian supplier — how?

Send quantity and destination country for a verified quote.

Why does it require hormone replacement therapy?

Mitotane destroys adrenal tissue as part of its mechanism, causing adrenal insufficiency that must be managed with steroid replacement.

Is it available for named-patient import?

Yes, this is the standard access pathway in most countries given how rare the treated cancer is.

Who supplies Mitotane from India?

WHO-GMP certified manufacturing with a focus on long-term supply continuity for ongoing patient treatment.