Austedo — Deutetrabenazine
Deutetrabenazine is a VMAT2 inhibitor prescribed by neurologists to reduce involuntary movements. The generic version gives hospitals, distributors, and access programmes a way to offer this specialist therapy at a lower cost than the originator brand (Austedo).
- Approved indications (adults): Chorea associated with Huntington’s disease; tardive dyskinesia
- Drug class: Vesicular monoamine transporter 2 (VMAT2) inhibitor
- How it works: Reversibly reduces monoamines such as dopamine, serotonin, norepinephrine, and histamine in nerve terminals, which settles the involuntary movements
- Formulation note: Deuterium atoms slow the drug’s breakdown, supporting steadier levels and a simpler dosing pattern
- Dosing pattern: Started low and increased gradually under specialist supervision, up to a maximum of 48 mg per day. Total daily doses of 12 mg or more are split into two doses with food
- Treatment duration: Usually long-term, so affordable and dependable supply matters
Key Product Facts
6 mg, 9 mg, 12 mg
Strength
60 Tablets
Pack Size
Deutetrabenazine
Active Ingredient
Neurology
Category
Enquire Now for Pricing
Price
Deutetrabenazine is a VMAT2 inhibitor prescribed by neurologists to reduce involuntary movements. The generic version gives hospitals, distributors, and access programmes a way to offer this specialist therapy at a lower cost than the originator brand (Austedo).
- Approved indications (adults): Chorea associated with Huntington’s disease; tardive dyskinesia
- Drug class: Vesicular monoamine transporter 2 (VMAT2) inhibitor
- How it works: Reversibly reduces monoamines such as dopamine, serotonin, norepinephrine, and histamine in nerve terminals, which settles the involuntary movements
- Formulation note: Deuterium atoms slow the drug’s breakdown, supporting steadier levels and a simpler dosing pattern
- Dosing pattern: Started low and increased gradually under specialist supervision, up to a maximum of 48 mg per day. Total daily doses of 12 mg or more are split into two doses with food
- Treatment duration: Usually long-term, so affordable and dependable supply matters
- Boxed warning: Depression and suicidal thoughts have been reported in Huntington’s disease patients. Mood must be assessed before starting and monitored throughout treatment
- Do not use in: Patients who are suicidal, whose depression is untreated or inadequately treated, or who have impaired liver function
- Interactions to avoid: Tetrabenazine, valbenazine, reserpine, and MAO inhibitors (at least 14 days gap after stopping an MAOI)
- Dose limit: Maximum 36 mg per day with strong CYP2D6 inhibitors (such as paroxetine, fluoxetine, bupropion) and in CYP2D6 poor metabolisers
- Heart rhythm: May prolong the QT interval, so caution is needed with other QT-prolonging medicines
- Other recognised risks: Drowsiness, restlessness (akathisia), parkinsonism, and, rarely, neuroleptic malignant syndrome
- Missed treatment: If treatment is missed for more than a week, the patient should consult the physician before restarting
- Pregnancy: Use only after the specialist has weighed benefit against risk
- Switching products: Any change between originator and generic should be made by the treating physician
| Document |
Status |
| Certificate of Analysis (batch-specific) |
Provided with every order |
| Certificate of Origin |
Provided with every order |
| GMP certification of the manufacturer |
Provided with every order |
| Material Safety Data Sheet |
Provided with every order |
| Bioequivalence / dissolution data |
On request, subject to manufacturer |
| CTD / ACTD dossier support |
On request, for market registration |
| Named-patient import documentation |
On request |
Availability: Current stock, strengths, and pricing are confirmed once you share your quantity and destination country. A verified quote is typically shared within 24 hours.
- Logistics: Standard export logistics by air or sea, with no cold chain required, which keeps freight cost low
- Active corridors: Southeast Asia, the GCC and Middle East, Africa, and Latin America
- Tracking: Full shipment tracking, with customs documentation support
- Order size: Flexible quantities for hospitals, distributors, and access programmes
What is generic Deutetrabenazine used for?
It treats chorea (involuntary movements) associated with Huntington’s disease and tardive dyskinesia in adults.
How is the generic different from the originator brand?
The active ingredient is the same. The generic is usually more affordable, and we request quality and bioequivalence data from the manufacturer.
How do I get a generic Deutetrabenazine price quote from a GMP-compliant Indian supplier?
Please share your required strength, quantity, and destination country. We will respond with a verified quote, usually within 24 hours.
Is generic Deutetrabenazine available in every country?
Availability depends on the molecule’s patent and registration position in each country. We check this before quoting.
Does it need cold chain shipping?
No. It is a room-temperature stable tablet and ships through standard export logistics.